A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report
Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant genetic condition characterized by the development of hamartoma-type intestinal polyposis and areas of skin pigmentation, among other signs. Additionally, the occurrence of solitary Peutz-Jeghers polyps is exceedingly rare. We present the cas...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-07, Vol.16 (7), p.e63943 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 7 |
| container_start_page | e63943 |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 16 |
| creator | Madera, Noelia Acevedo, Noemí González-Peralta, Carmen Castro, Rafael Mezquita-Luna, Vismelis |
| description | Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant genetic condition characterized by the development of hamartoma-type intestinal polyposis and areas of skin pigmentation, among other signs. Additionally, the occurrence of solitary Peutz-Jeghers polyps is exceedingly rare. We present the case of a 50-year-old female with a medical history of hypothyroidism, chronic gastritis, and dyslipidemia, who presented with dyspeptic symptoms and occasional rectal bleeding. Endoscopic examination revealed a solitary hamartomatous polyp in the gastric body and other gastrointestinal abnormalities. The patient underwent treatment and is being monitored with regular endoscopic studies and evaluations for other potential neoplasms. This case underscores the importance of considering the syndrome as a potential differential diagnosis. It emphasizes the necessity of a multidisciplinary approach to managing and monitoring such cases, particularly the early detection of possible neoplasms. |
| doi_str_mv | 10.7759/cureus.63943 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11300189</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3089881050</sourcerecordid><originalsourceid>FETCH-LOGICAL-c300t-6f845c45bf7f046713b17cc8cdd2863cd310e29a5834f3fa999a66d00cce35be3</originalsourceid><addsrcrecordid>eNpdkc1rGzEQxUVJaEziW89F0EsO3WS02tVKuQTXpPkgYNOPs5C1s_GG9cqRtAX3r48auyYJDMzA_Hi8xyPkE4OzqirVuR08DuFMcFXwD2SUMyEzyWRx8Oo-IuMQHgGAQZVDBR_JEVcM0sCIzCb0p-vaaPyGznGIf7M7fFiiD_TGrIyPbmWiGwKdu26zpm1P4xLptQnRt5Z-c_Xmgk7o1ASkP3DtfDwhh43pAo53-5j8_n71a3qT3c-ub6eT-8xygJiJRhalLcpFUzVQiIrxBauslbaucym4rTkDzJUpJS8a3hillBGiBrAWeblAfkwut7rrYbHC2mIfven02rfJ9UY70-q3n75d6gf3RzOWDDCpksLpTsG7pwFD1Ks2WOw602NKrDlIJSWDEhL65R366Abfp3yJUirPhcjzRH3dUta7EDw2ezcM9L-29LYt_dJWwj-_TrCH_3fDnwEQ-JCm</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3099226622</pqid></control><display><type>article</type><title>A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report</title><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Madera, Noelia ; Acevedo, Noemí ; González-Peralta, Carmen ; Castro, Rafael ; Mezquita-Luna, Vismelis</creator><creatorcontrib>Madera, Noelia ; Acevedo, Noemí ; González-Peralta, Carmen ; Castro, Rafael ; Mezquita-Luna, Vismelis</creatorcontrib><description>Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant genetic condition characterized by the development of hamartoma-type intestinal polyposis and areas of skin pigmentation, among other signs. Additionally, the occurrence of solitary Peutz-Jeghers polyps is exceedingly rare. We present the case of a 50-year-old female with a medical history of hypothyroidism, chronic gastritis, and dyslipidemia, who presented with dyspeptic symptoms and occasional rectal bleeding. Endoscopic examination revealed a solitary hamartomatous polyp in the gastric body and other gastrointestinal abnormalities. The patient underwent treatment and is being monitored with regular endoscopic studies and evaluations for other potential neoplasms. This case underscores the importance of considering the syndrome as a potential differential diagnosis. It emphasizes the necessity of a multidisciplinary approach to managing and monitoring such cases, particularly the early detection of possible neoplasms.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.63943</identifier><identifier>PMID: 39109100</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Biopsy ; Breast cancer ; Case reports ; Constipation ; Endoscopy ; Family medical history ; Gastroenterology ; Genetic counseling ; Genetics ; Hiatal hernias ; Immunohistochemistry ; Internal Medicine ; Mammography ; Mutation ; Pathology ; Polyps ; Smooth muscle ; Surveillance ; Thyroid gland ; Tumors</subject><ispartof>Curēus (Palo Alto, CA), 2024-07, Vol.16 (7), p.e63943</ispartof><rights>Copyright © 2024, Madera et al.</rights><rights>Copyright © 2024, Madera et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Madera et al. 2024 Madera et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-6f845c45bf7f046713b17cc8cdd2863cd310e29a5834f3fa999a66d00cce35be3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300189/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300189/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39109100$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Madera, Noelia</creatorcontrib><creatorcontrib>Acevedo, Noemí</creatorcontrib><creatorcontrib>González-Peralta, Carmen</creatorcontrib><creatorcontrib>Castro, Rafael</creatorcontrib><creatorcontrib>Mezquita-Luna, Vismelis</creatorcontrib><title>A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant genetic condition characterized by the development of hamartoma-type intestinal polyposis and areas of skin pigmentation, among other signs. Additionally, the occurrence of solitary Peutz-Jeghers polyps is exceedingly rare. We present the case of a 50-year-old female with a medical history of hypothyroidism, chronic gastritis, and dyslipidemia, who presented with dyspeptic symptoms and occasional rectal bleeding. Endoscopic examination revealed a solitary hamartomatous polyp in the gastric body and other gastrointestinal abnormalities. The patient underwent treatment and is being monitored with regular endoscopic studies and evaluations for other potential neoplasms. This case underscores the importance of considering the syndrome as a potential differential diagnosis. It emphasizes the necessity of a multidisciplinary approach to managing and monitoring such cases, particularly the early detection of possible neoplasms.</description><subject>Biopsy</subject><subject>Breast cancer</subject><subject>Case reports</subject><subject>Constipation</subject><subject>Endoscopy</subject><subject>Family medical history</subject><subject>Gastroenterology</subject><subject>Genetic counseling</subject><subject>Genetics</subject><subject>Hiatal hernias</subject><subject>Immunohistochemistry</subject><subject>Internal Medicine</subject><subject>Mammography</subject><subject>Mutation</subject><subject>Pathology</subject><subject>Polyps</subject><subject>Smooth muscle</subject><subject>Surveillance</subject><subject>Thyroid gland</subject><subject>Tumors</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkc1rGzEQxUVJaEziW89F0EsO3WS02tVKuQTXpPkgYNOPs5C1s_GG9cqRtAX3r48auyYJDMzA_Hi8xyPkE4OzqirVuR08DuFMcFXwD2SUMyEzyWRx8Oo-IuMQHgGAQZVDBR_JEVcM0sCIzCb0p-vaaPyGznGIf7M7fFiiD_TGrIyPbmWiGwKdu26zpm1P4xLptQnRt5Z-c_Xmgk7o1ASkP3DtfDwhh43pAo53-5j8_n71a3qT3c-ub6eT-8xygJiJRhalLcpFUzVQiIrxBauslbaucym4rTkDzJUpJS8a3hillBGiBrAWeblAfkwut7rrYbHC2mIfven02rfJ9UY70-q3n75d6gf3RzOWDDCpksLpTsG7pwFD1Ks2WOw602NKrDlIJSWDEhL65R366Abfp3yJUirPhcjzRH3dUta7EDw2ezcM9L-29LYt_dJWwj-_TrCH_3fDnwEQ-JCm</recordid><startdate>20240706</startdate><enddate>20240706</enddate><creator>Madera, Noelia</creator><creator>Acevedo, Noemí</creator><creator>González-Peralta, Carmen</creator><creator>Castro, Rafael</creator><creator>Mezquita-Luna, Vismelis</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240706</creationdate><title>A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report</title><author>Madera, Noelia ; Acevedo, Noemí ; González-Peralta, Carmen ; Castro, Rafael ; Mezquita-Luna, Vismelis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c300t-6f845c45bf7f046713b17cc8cdd2863cd310e29a5834f3fa999a66d00cce35be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Biopsy</topic><topic>Breast cancer</topic><topic>Case reports</topic><topic>Constipation</topic><topic>Endoscopy</topic><topic>Family medical history</topic><topic>Gastroenterology</topic><topic>Genetic counseling</topic><topic>Genetics</topic><topic>Hiatal hernias</topic><topic>Immunohistochemistry</topic><topic>Internal Medicine</topic><topic>Mammography</topic><topic>Mutation</topic><topic>Pathology</topic><topic>Polyps</topic><topic>Smooth muscle</topic><topic>Surveillance</topic><topic>Thyroid gland</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Madera, Noelia</creatorcontrib><creatorcontrib>Acevedo, Noemí</creatorcontrib><creatorcontrib>González-Peralta, Carmen</creatorcontrib><creatorcontrib>Castro, Rafael</creatorcontrib><creatorcontrib>Mezquita-Luna, Vismelis</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Madera, Noelia</au><au>Acevedo, Noemí</au><au>González-Peralta, Carmen</au><au>Castro, Rafael</au><au>Mezquita-Luna, Vismelis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-07-06</date><risdate>2024</risdate><volume>16</volume><issue>7</issue><spage>e63943</spage><pages>e63943-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant genetic condition characterized by the development of hamartoma-type intestinal polyposis and areas of skin pigmentation, among other signs. Additionally, the occurrence of solitary Peutz-Jeghers polyps is exceedingly rare. We present the case of a 50-year-old female with a medical history of hypothyroidism, chronic gastritis, and dyslipidemia, who presented with dyspeptic symptoms and occasional rectal bleeding. Endoscopic examination revealed a solitary hamartomatous polyp in the gastric body and other gastrointestinal abnormalities. The patient underwent treatment and is being monitored with regular endoscopic studies and evaluations for other potential neoplasms. This case underscores the importance of considering the syndrome as a potential differential diagnosis. It emphasizes the necessity of a multidisciplinary approach to managing and monitoring such cases, particularly the early detection of possible neoplasms.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>39109100</pmid><doi>10.7759/cureus.63943</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2024-07, Vol.16 (7), p.e63943 |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11300189 |
| source | PubMed Central; PubMed Central Open Access |
| subjects | Biopsy Breast cancer Case reports Constipation Endoscopy Family medical history Gastroenterology Genetic counseling Genetics Hiatal hernias Immunohistochemistry Internal Medicine Mammography Mutation Pathology Polyps Smooth muscle Surveillance Thyroid gland Tumors |
| title | A Solitary Peutz-Jeghers Hamartomatous Polyp in the Gastric Body: A Case Report |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T21%3A03%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Solitary%20Peutz-Jeghers%20Hamartomatous%20Polyp%20in%20the%20Gastric%20Body:%20A%20Case%20Report&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Madera,%20Noelia&rft.date=2024-07-06&rft.volume=16&rft.issue=7&rft.spage=e63943&rft.pages=e63943-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.63943&rft_dat=%3Cproquest_pubme%3E3089881050%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3099226622&rft_id=info:pmid/39109100&rfr_iscdi=true |