BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development

Ligand-binding assays (LBAs) rely on the reversible, noncovalent binding between the analyte of interest and the assay reagents, and understanding their dynamic equilibrium is key to building robust LBA methods. Although the dynamic interplay of free and bound fractions can be calculated using mathe...

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Veröffentlicht in:	Bioanalysis 2024-06, Vol.16 (11), p.519-533
Hauptverfasser:	Dejager, Lien, Banton, Sophia, Marques, Patricia, Rinikova, Gabriela, Lory, Sabrina, Hickford, Elizabeth S, Martin-Hamka, Carole, Penney, Mark, Grootjans, Sasker
Format:	Artikel
Sprache:	eng
Schlagworte:	assay development binding kinetics and interactions Computer Simulation free web-based service Humans ligand-binding assay Ligands Method pharmacokinetics Protein Binding simulation tool Software
Online-Zugang:	Volltext
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