Silicone dressing combined with topical oxygen therapy alleviates incontinence‐associated dermatitis via NF‐κB p65/STAT1 signaling pathway

Background Incontinence‐associated dermatitis (IAD) is a tough problem in clinical settings, not only increasing the risk of complications like catheter‐related urinary tract infections and pressure ulcers in elderly and critically ill patients, but also prolonging hospital stays, raising hospital c...

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Veröffentlicht in:	Skin research and technology 2024-08, Vol.30 (8), p.e13888-n/a
Hauptverfasser:	Chen, Guiyu an, Chen, Yingxun, Zhang, Yan, Zheng, Shufeng, Zhu, Louying, Ding, Mingxing
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animal models Animals Bandages Dermatitis Dermatitis - etiology Dermatitis - therapy Disease Models, Animal Enzyme-linked immunosorbent assay Gene expression Histology Hospital costs Hospitals Immunofluorescence incontinence‐associated dermatitis Inflammation Male Medical instruments nf‐κb p65/stat1 pathway Original Oxygen Oxygen - administration & dosage Oxygen therapy Platelet-derived growth factor Rats Rats, Sprague-Dawley Signal transduction Signal Transduction - drug effects silicone dressing combined with topical oxygen therapy Silicones Skin Stat1 protein STAT1 Transcription Factor - metabolism Therapy Transcription Factor RelA - metabolism Trypsin Ulcers Urinary Incontinence - etiology Urinary Incontinence - therapy Urinary tract Vascular endothelial growth factor Western blotting Wound healing
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