Role of Long Intergenic Nonprotein-Coding RNA 00511 in Nod-Like Receptor Protein Pyrin Domain 3-Induced Chondrocyte Pyroptosis via the MicroRNA-9-5p/FUT1 Axis

This study aimed to determine the function of LINC00511 in Nod-Like Receptor Pyrin Domain 3 inflammasome-mediated chondrocyte pyroptosis via the regulation of miR-9-5p and FUT 1. Chondrocyte inflammatory injury was induced by treating chondrocytes with LPS. Afterwards, the levels of IL-1β and IL-18,...

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Veröffentlicht in:	Journal of microbiology and biotechnology 2024-07, Vol.34 (7), p.1511-1521
Hauptverfasser:	Zhai, Tianjun, Zhang, Zengqiao, Hu, Xiaoshen, He, Dongyi, Feng, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caspase 1 - genetics Caspase 1 - metabolism Cell Line Cell Survival Chondrocytes - metabolism Fucosyltransferases - genetics Fucosyltransferases - metabolism Humans Inflammasomes - metabolism Interleukin-18 - genetics Interleukin-18 - metabolism Interleukin-1beta - metabolism Lipopolysaccharides Mice MicroRNAs - genetics MicroRNAs - metabolism NLR Family, Pyrin Domain-Containing 3 Protein - genetics NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Pyroptosis Research article RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism
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