Comparative genomics of Cryptosporidium parvum reveals the emergence of an outbreak-associated population in Europe and its spread to the United States

The zoonotic parasite is a global cause of gastrointestinal disease in humans and ruminants. Sequence analysis of the highly polymorphic gene enabled the classification of isolates into multiple groups (e.g., IIa, IIc, Id) and a large number of subtypes. In Europe, subtype IIaA15G2R1 is largely pred...

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Veröffentlicht in:	Genome research 2024-06, Vol.34 (6), p.877-887
Hauptverfasser:	Bellinzona, Greta, Nardi, Tiago, Castelli, Michele, Batisti Biffignandi, Gherard, Adjou, Karim, Betson, Martha, Blanchard, Yannick, Bujila, Ioana, Chalmers, Rachel, Davidson, Rebecca, D'Avino, Nicoletta, Enbom, Tuulia, Gomes, Jacinto, Karadjian, Gregory, Klotz, Christian, Östlund, Emma, Plutzer, Judith, Rimhanen-Finne, Ruska, Robinson, Guy, Sannella, Anna Rosa, Sroka, Jacek, Stensvold, Christen Rune, Troell, Karin, Vatta, Paolo, Zalewska, Barbora, Bandi, Claudio, Sassera, Davide, Cacciò, Simone M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals China - epidemiology Cryptosporidiosis - epidemiology Cryptosporidiosis - parasitology Cryptosporidium parvum Cryptosporidium parvum - genetics Disease Outbreaks Egypt - epidemiology Epidemics Europe - epidemiology Gastrointestinal diseases Genome, Protozoan Genomic analysis Genomics Genomics - methods Humans Life Sciences Nucleotide sequence Outbreaks Phylogeny Polymorphism, Single Nucleotide Population genetics Population structure Sequence analysis Single-nucleotide polymorphism United States - epidemiology Whole Genome Sequencing - methods Zoonoses
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