Conservation of C4BP-binding sequence patterns in Streptococcus pyogenes M and Enn proteins

Antigenically sequence variable M proteins of the major bacterial pathogen Streptococcus pyogenes (Strep A) are responsible for recruiting human C4b-binding protein (C4BP) to the bacterial surface, which enables Strep A to evade destruction by the immune system. The most sequence divergent portion o...

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Veröffentlicht in:	The Journal of biological chemistry 2024-07, Vol.300 (7), p.107478, Article 107478
Hauptverfasser:	Kolesiński, Piotr, McGowan, Matthew, Botteaux, Anne, Smeesters, Pierre R., Ghosh, Partho
Format:	Artikel
Sprache:	eng
Schlagworte:	C4BP cross-reactivity immunogen M protein Streptococcus pyogenes
Online-Zugang:	Volltext
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