Immediate myeloid depot for SARS-CoV-2 in the human lung

In the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, epithelial populations in the distal lung expressing Angiotensin-converting enzyme 2 (ACE2) are infrequent, and therefore, the model of viral expansion and immune cell engagement remains incompletely under...

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Veröffentlicht in:	Science advances 2024-08, Vol.10 (31), p.eadm8836
Hauptverfasser:	Magnen, Mélia, You, Ran, Rao, Arjun A, Davis, Ryan T, Rodriguez, Lauren, Bernard, Olivier, Simoneau, Camille R, Hysenaj, Lisiena, Hu, Kenneth H, Maishan, Mazharul, Conrad, Catharina, Gbenedio, Oghenekevwe M, Samad, Bushra, Consortium, The Ucsf Comet, Love, Christina, Woodruff, Prescott G, Erle, David J, Hendrickson, Carolyn M, Calfee, Carolyn S, Matthay, Michael A, Roose, Jeroen P, Sil, Anita, Ott, Melanie, Langelier, Charles R, Krummel, Matthew F, Looney, Mark R
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme 2 - metabolism Biomedicine and Life Sciences Coronavirus COVID-19 - immunology COVID-19 - virology Humans Immunology Lung - immunology Lung - pathology Lung - virology Macrophages, Alveolar - immunology Macrophages, Alveolar - metabolism Macrophages, Alveolar - virology Myeloid Cells - immunology Myeloid Cells - metabolism Myeloid Cells - virology SARS-CoV-2 - physiology SciAdv r-articles Spike Glycoprotein, Coronavirus - immunology Spike Glycoprotein, Coronavirus - metabolism Viral Tropism Virology Virus Internalization
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