Prognosis of polymerase epsilon (POLE) mutation in high-grade endometrioid endometrial cancer: Systematic review and meta-analysis

POLE mutated endometrial carcinomas may represent a subspecific type of tumors harboring a more favorable prognosis. Grade 3 (G3 or high-grade) endometrioid endometrial carcinomas remain a clinical dilemma, with some tumors behaving as the low-grade counterparts and others presenting a more aggressi...

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Veröffentlicht in:	Gynecologic oncology 2024-03, Vol.182, p.99-107
Hauptverfasser:	Casanova, Joao, Duarte, Gonçalo Silva, da Costa, Ana Gomes, Catarino, Ana, Nave, Mónica, Antunes, Telma, Serra, Sofia Silvério, Dias, Sara Simões, Abu-Rustum, Nadeem, Lima, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Endometrioid - pathology Endometrial cancer Endometrial Neoplasms - pathology Endometrioid Female High-grade Humans Meta-analysis Mutation Neoplasm Grading POLE Poly-ADP-Ribose Binding Proteins - genetics Prognosis Systematic review
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