Protective role of SARS-CoV-2 anti-S IgG against breakthrough infections among European healthcare workers during pre and post-Omicron surge—ORCHESTRA project

Purpose Anti SARS-CoV-2 vaccination initially showed high effectiveness in preventing COVID-19. However, after the surge of variants of concern, the effectiveness dropped. Several studies investigated if this was related to the decrease of the humoral response over time; however, this issue is still...

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Veröffentlicht in:	Infection 2024-08, Vol.52 (4), p.1347-1356
Hauptverfasser:	Spiteri, Gianluca, D’Agostini, Marika, Abedini, Mahsa, Ditano, Giorgia, Collatuzzo, Giulia, Boffetta, Paolo, Vimercati, Luigi, Sansone, Emanuele, De Palma, Giuseppe, Modenese, Alberto, Gobba, Fabriziomaria, Liviero, Filippo, Moretto, Angelo, dell’Omo, Marco, Fiordi, Tiziana, Larese Filon, Francesca, Mauro, Marcella, Violán, Concepción, Mates, Dana, Oravec Bérešová, Jana, Monaco, Maria Grazia Lourdes, Carta, Angela, Verlato, Giuseppe, Porru, Stefano
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Viral - blood Breakthrough Infections Cell-mediated immunity COVID-19 COVID-19 - immunology COVID-19 - prevention & control COVID-19 Vaccines - administration & dosage COVID-19 Vaccines - immunology Effectiveness Europe - epidemiology Family Medicine Female General Practice Health hazards Health Personnel - statistics & numerical data Health risks Humans Immune response (humoral) Immunization, Secondary Immunoglobulin G Immunoglobulin G - blood Immunology Infections Infectious Diseases Internal Medicine Male Medical personnel Medicine Medicine & Public Health Middle Aged Risk analysis SARS-CoV-2 - immunology Serology Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - immunology Vaccine efficacy
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