Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure
Cardiovascular disease is the leading cause of death worldwide. Existing methods for continuous, noninvasive blood pressure (BP) monitoring suffer from poor accuracy, uncomfortable form factors, or a need for frequent calibration, limiting their adoption. We introduce a new framework for continuous...
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| Veröffentlicht in: | PNAS nexus 2024-07, Vol.3 (7), p.pgae252 |
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| creator | Jimenez, Raymond Yurk, Dominic Dell, Steven Rutledge, Austin C Fu, Matt K Dempsey, William P Abu-Mostafa, Yaser Rajagopal, Aditya Brinley Rajagopal, Alaina |
| description | Cardiovascular disease is the leading cause of death worldwide. Existing methods for continuous, noninvasive blood pressure (BP) monitoring suffer from poor accuracy, uncomfortable form factors, or a need for frequent calibration, limiting their adoption. We introduce a new framework for continuous BP measurement that is noninvasive and calibration-free called resonance sonomanometry. The method uses ultrasound imaging to measure both the arterial dimensions and artery wall resonances that are induced by acoustic stimulation, which offers a direct measure of BP by a fully determined physical model. The approach and model are validated in vitro using arterial mock-ups and then in multiple arteries in human subjects. This approach offers the promise of robust continuous BP measurements, providing significant benefits for early diagnosis and treatment of cardiovascular disease. |
| doi_str_mv | 10.1093/pnasnexus/pgae252 |
| format | Article |
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This approach offers the promise of robust continuous BP measurements, providing significant benefits for early diagnosis and treatment of cardiovascular disease.</description><subject>Biological, Health, and Medical Sciences</subject><subject>Blood pressure</subject><subject>Cardiovascular diseases</subject><subject>Care and treatment</subject><subject>Diagnosis</subject><subject>Measurement</subject><subject>Patient monitoring equipment</subject><subject>Ultrasound imaging</subject><issn>2752-6542</issn><issn>2752-6542</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNptUV1rFTEQDaK0pfYH9EUWfPGht83k4yb7JKXYKhQU0eeQzU6ukd1kTXYv9t835V4vLcgQZpg55zCTQ8g50EugLb-aoi0R_y7latpYZJK9IidMSbZaS8FeP6uPyVkpvymlTCkAIY_IMW-pBqXlCfn2HUuKNjpsak6jrQ_n_ND4lJuYYohbW8IWLxqX4hzikpbSjLU_pxzipkm-6YaU-mbKWMqS8S154-1Q8GyfT8nP208_bj6v7r_efbm5vl85Ltp5BUK1lPoOaC-p6rxHVHVh1M5ihyjWtpUaOs69oMrTdQeid6xnVvRKKtHzU_Jxpzst3Yi9wzhnO5gph9HmB5NsMC8nMfwym7Q1AEwrraAqfNgr5PRnwTKbMRSHw2Aj1isNp3rNNWsVr9D3O-jGDmhC9KlKuie4udZUSQEAbUVd_gdVo8cx1O9DH2r_BQF2BJdTKRn9YX2g5slkczDZ7E2unHfP7z4w_lnKHwEmDahk</recordid><startdate>202407</startdate><enddate>202407</enddate><creator>Jimenez, Raymond</creator><creator>Yurk, Dominic</creator><creator>Dell, Steven</creator><creator>Rutledge, Austin C</creator><creator>Fu, Matt K</creator><creator>Dempsey, William P</creator><creator>Abu-Mostafa, Yaser</creator><creator>Rajagopal, Aditya</creator><creator>Brinley Rajagopal, Alaina</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2276-4189</orcidid><orcidid>https://orcid.org/0000-0002-2652-0309</orcidid><orcidid>https://orcid.org/0000-0001-5845-023X</orcidid></search><sort><creationdate>202407</creationdate><title>Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure</title><author>Jimenez, Raymond ; Yurk, Dominic ; Dell, Steven ; Rutledge, Austin C ; Fu, Matt K ; Dempsey, William P ; Abu-Mostafa, Yaser ; Rajagopal, Aditya ; Brinley Rajagopal, Alaina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-147900fb10d507bffee7752e8caebee46a9581b33f407f06b14dc2d2a4d7574d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Biological, Health, and Medical Sciences</topic><topic>Blood pressure</topic><topic>Cardiovascular diseases</topic><topic>Care and treatment</topic><topic>Diagnosis</topic><topic>Measurement</topic><topic>Patient monitoring equipment</topic><topic>Ultrasound imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jimenez, Raymond</creatorcontrib><creatorcontrib>Yurk, Dominic</creatorcontrib><creatorcontrib>Dell, Steven</creatorcontrib><creatorcontrib>Rutledge, Austin C</creatorcontrib><creatorcontrib>Fu, Matt K</creatorcontrib><creatorcontrib>Dempsey, William P</creatorcontrib><creatorcontrib>Abu-Mostafa, Yaser</creatorcontrib><creatorcontrib>Rajagopal, Aditya</creatorcontrib><creatorcontrib>Brinley Rajagopal, Alaina</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>PNAS nexus</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jimenez, Raymond</au><au>Yurk, Dominic</au><au>Dell, Steven</au><au>Rutledge, Austin C</au><au>Fu, Matt K</au><au>Dempsey, William P</au><au>Abu-Mostafa, Yaser</au><au>Rajagopal, Aditya</au><au>Brinley Rajagopal, Alaina</au><au>Desai, Tejal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure</atitle><jtitle>PNAS nexus</jtitle><addtitle>PNAS Nexus</addtitle><date>2024-07</date><risdate>2024</risdate><volume>3</volume><issue>7</issue><spage>pgae252</spage><pages>pgae252-</pages><issn>2752-6542</issn><eissn>2752-6542</eissn><abstract>Cardiovascular disease is the leading cause of death worldwide. 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| source | DOAJ Directory of Open Access Journals; Oxford Journals Open Access Collection; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Biological, Health, and Medical Sciences Blood pressure Cardiovascular diseases Care and treatment Diagnosis Measurement Patient monitoring equipment Ultrasound imaging |
| title | Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure |
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