Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review
Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. G. lucidum spores (GLS) are tiny germ cells released from the mushroom cap during the mature stage of growth. They contain all the genetic active substances of G. lucidum. G. lucidum spore...
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| Veröffentlicht in: | Chinese herbal medicines 2024-07, Vol.16 (3), p.375-391 |
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| creator | Liu, Jianying Zhang, Binzhi Wang, Leqi Li, Shasha Long, Qinqiang Xiao, Xue |
| description | Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. G. lucidum spores (GLS) are tiny germ cells released from the mushroom cap during the mature stage of growth. They contain all the genetic active substances of G. lucidum. G. lucidum spore oil (GLSO) is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO2 extraction technology. GLSO contains fatty acids, Ganoderma triterpenes, sterols and other bioactive compounds. Previous studies have demonstrated that GLSO has a wide range of pharmacological properties, including anti-tumor, anti-aging, neuroprotection, immunomodulation, hepatoprotection and modulation of metabolic diseases. This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components, extraction and processing techniques, pharmacological effects and safety evaluation. This provides a solid foundation for further research and application of GLSO. |
| doi_str_mv | 10.1016/j.chmed.2023.09.007 |
| format | Article |
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G. lucidum spores (GLS) are tiny germ cells released from the mushroom cap during the mature stage of growth. They contain all the genetic active substances of G. lucidum. G. lucidum spore oil (GLSO) is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO2 extraction technology. GLSO contains fatty acids, Ganoderma triterpenes, sterols and other bioactive compounds. Previous studies have demonstrated that GLSO has a wide range of pharmacological properties, including anti-tumor, anti-aging, neuroprotection, immunomodulation, hepatoprotection and modulation of metabolic diseases. This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components, extraction and processing techniques, pharmacological effects and safety evaluation. 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This provides a solid foundation for further research and application of GLSO.</description><subject>anti-aging</subject><subject>anti-tumor</subject><subject>bioactive components</subject><subject>Ganoderma lucidum spore oil</subject><subject>hepatoprotection</subject><subject>immune regulation</subject><subject>pharmacological properties</subject><subject>Review</subject><issn>1674-6384</issn><issn>2589-3610</issn><issn>2589-3610</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kU9v1DAQxS0EoqvST4CEfORAgv8kToyEUKloQarEBc6Wdzy761ViBzvZqt8eL9tWcMEXH-bNm5n3I-Q1ZzVnXL3f17Ab0dWCCVkzXTPWPSMr0fa6koqz52TFVddUSvbNGbnIec_KU1xI0bwkZ1KzTnCtViR99tHC7A9IIY5TDBjm_I5OO5tGC3GIWw92oFOKE6bZY6Y2OLoEh2m492FLR4SdDT6PNG7ojQ2xVEZLhwW8W0aap5iQRj98oJc04cHj3SvyYmOHjBcP_zn5ef3lx9XX6vb7zbery9sKGsXmCi12PYNGSiVE60TnZMsU07rc4JoONeub9Vo43sNGizW0AMgsQ8UtKtBMnpNPJ99pWZeooFyW7GCm5Eeb7k203vxbCX5ntvFgOBe9FLIpDm8fHFL8tWCezegz4DDYgHHJRrK-Vf1xoSKVJymkmHPCzdMczsyRmNmbP8TMkZhh2hRipevN3ys-9TzyKYKPJwGWoEp4yWTwGACdTwizcdH_d8Bv1o2q3Q</recordid><startdate>20240701</startdate><enddate>20240701</enddate><creator>Liu, Jianying</creator><creator>Zhang, Binzhi</creator><creator>Wang, Leqi</creator><creator>Li, Shasha</creator><creator>Long, Qinqiang</creator><creator>Xiao, Xue</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240701</creationdate><title>Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review</title><author>Liu, Jianying ; Zhang, Binzhi ; Wang, Leqi ; Li, Shasha ; Long, Qinqiang ; Xiao, Xue</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-eae780c4336225d27d3506099232d47e9084bb2d18cf92bc5cce0a0e61ae6c903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>anti-aging</topic><topic>anti-tumor</topic><topic>bioactive components</topic><topic>Ganoderma lucidum spore oil</topic><topic>hepatoprotection</topic><topic>immune regulation</topic><topic>pharmacological properties</topic><topic>Review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Jianying</creatorcontrib><creatorcontrib>Zhang, Binzhi</creatorcontrib><creatorcontrib>Wang, Leqi</creatorcontrib><creatorcontrib>Li, Shasha</creatorcontrib><creatorcontrib>Long, Qinqiang</creatorcontrib><creatorcontrib>Xiao, Xue</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chinese herbal medicines</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Jianying</au><au>Zhang, Binzhi</au><au>Wang, Leqi</au><au>Li, Shasha</au><au>Long, Qinqiang</au><au>Xiao, Xue</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review</atitle><jtitle>Chinese herbal medicines</jtitle><addtitle>Chin Herb Med</addtitle><date>2024-07-01</date><risdate>2024</risdate><volume>16</volume><issue>3</issue><spage>375</spage><epage>391</epage><pages>375-391</pages><issn>1674-6384</issn><issn>2589-3610</issn><eissn>2589-3610</eissn><abstract>Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment. G. lucidum spores (GLS) are tiny germ cells released from the mushroom cap during the mature stage of growth. They contain all the genetic active substances of G. lucidum. G. lucidum spore oil (GLSO) is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO2 extraction technology. GLSO contains fatty acids, Ganoderma triterpenes, sterols and other bioactive compounds. Previous studies have demonstrated that GLSO has a wide range of pharmacological properties, including anti-tumor, anti-aging, neuroprotection, immunomodulation, hepatoprotection and modulation of metabolic diseases. This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components, extraction and processing techniques, pharmacological effects and safety evaluation. 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| subjects | anti-aging anti-tumor bioactive components Ganoderma lucidum spore oil hepatoprotection immune regulation pharmacological properties Review |
| title | Bioactive components, pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil: A review |
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