Contemporary Role of Open Left Thoracoabdominal Approach in Esophageal Malignancy Treatment
Despite the widespread use of minimally invasive techniques, open left thoracoabdominal esophagectomy (LTE) can offer excellent visualization and adaptability. The current study aimed to present and evaluate the outcomes related to an open LTE in esophageal malignancy treatment. A retrospective coho...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-06, Vol.16 (6), p.e62922 |
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| creator | Dellaportas, Dionysios Margaris, Ioannis Latsonas, Panagiotis Pikouli, Anastasia Vlachos, Iakovos Papakonstantinou, Dimitrios Pararas, Nikolaos Nastos, Constantinos Myoteri, Despoina Pikoulis, Emmanuel |
| description | Despite the widespread use of minimally invasive techniques, open left thoracoabdominal esophagectomy (LTE) can offer excellent visualization and adaptability. The current study aimed to present and evaluate the outcomes related to an open LTE in esophageal malignancy treatment.
A retrospective cohort analysis of data collected from two institutions was performed, including patients with distal esophageal or junctional tumors who underwent open LTE between November 2018 and December 2023.
Twenty-two patients were included (16 males; mean age 62.8 years). Postoperative complications occurred in eight patients (36%), with pulmonary complications being the most prevalent (seven patients; 32%). One patient experienced a clinical anastomotic leak. No reoperations or escalation to a higher level of care were required. In-hospital and 30-day mortality were zero. Tumor cells were found at the surgical margins in six patients (27%). The mean lymph node yield was 27. During the follow-up period, there were nine deaths and 11 cases of disease recurrence. Isolated locoregional recurrence was seen in five patients (23%). The one-year and two-year overall survival rates were 79% and 47%, respectively.
In selected cases, open LTE remains a valid and safe operation with acceptable morbidity and oncological efficacy. |
| doi_str_mv | 10.7759/cureus.62922 |
| format | Article |
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A retrospective cohort analysis of data collected from two institutions was performed, including patients with distal esophageal or junctional tumors who underwent open LTE between November 2018 and December 2023.
Twenty-two patients were included (16 males; mean age 62.8 years). Postoperative complications occurred in eight patients (36%), with pulmonary complications being the most prevalent (seven patients; 32%). One patient experienced a clinical anastomotic leak. No reoperations or escalation to a higher level of care were required. In-hospital and 30-day mortality were zero. Tumor cells were found at the surgical margins in six patients (27%). The mean lymph node yield was 27. During the follow-up period, there were nine deaths and 11 cases of disease recurrence. Isolated locoregional recurrence was seen in five patients (23%). The one-year and two-year overall survival rates were 79% and 47%, respectively.
In selected cases, open LTE remains a valid and safe operation with acceptable morbidity and oncological efficacy.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.62922</identifier><identifier>PMID: 39040781</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Cancer therapies ; Chemotherapy ; Comorbidity ; Endoscopy ; Esophageal cancer ; Esophagus ; Fistula ; Gastroenterology ; Gastrointestinal surgery ; General Surgery ; Hospitals ; Length of stay ; Morbidity ; Mortality ; Ostomy ; Patients ; Pneumonia ; Statistical analysis ; Surgical anastomosis ; Tomography ; Tumors ; Veins & arteries</subject><ispartof>Curēus (Palo Alto, CA), 2024-06, Vol.16 (6), p.e62922</ispartof><rights>Copyright © 2024, Dellaportas et al.</rights><rights>Copyright © 2024, Dellaportas et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Dellaportas et al. 2024 Dellaportas et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-11984ae04789c0d725586ed641ce2e9587d7275105ff0686ab4320031de4187d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262707/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262707/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39040781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dellaportas, Dionysios</creatorcontrib><creatorcontrib>Margaris, Ioannis</creatorcontrib><creatorcontrib>Latsonas, Panagiotis</creatorcontrib><creatorcontrib>Pikouli, Anastasia</creatorcontrib><creatorcontrib>Vlachos, Iakovos</creatorcontrib><creatorcontrib>Papakonstantinou, Dimitrios</creatorcontrib><creatorcontrib>Pararas, Nikolaos</creatorcontrib><creatorcontrib>Nastos, Constantinos</creatorcontrib><creatorcontrib>Myoteri, Despoina</creatorcontrib><creatorcontrib>Pikoulis, Emmanuel</creatorcontrib><title>Contemporary Role of Open Left Thoracoabdominal Approach in Esophageal Malignancy Treatment</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Despite the widespread use of minimally invasive techniques, open left thoracoabdominal esophagectomy (LTE) can offer excellent visualization and adaptability. The current study aimed to present and evaluate the outcomes related to an open LTE in esophageal malignancy treatment.
A retrospective cohort analysis of data collected from two institutions was performed, including patients with distal esophageal or junctional tumors who underwent open LTE between November 2018 and December 2023.
Twenty-two patients were included (16 males; mean age 62.8 years). Postoperative complications occurred in eight patients (36%), with pulmonary complications being the most prevalent (seven patients; 32%). One patient experienced a clinical anastomotic leak. No reoperations or escalation to a higher level of care were required. In-hospital and 30-day mortality were zero. Tumor cells were found at the surgical margins in six patients (27%). The mean lymph node yield was 27. During the follow-up period, there were nine deaths and 11 cases of disease recurrence. Isolated locoregional recurrence was seen in five patients (23%). The one-year and two-year overall survival rates were 79% and 47%, respectively.
In selected cases, open LTE remains a valid and safe operation with acceptable morbidity and oncological efficacy.</description><subject>Abdomen</subject><subject>Cancer therapies</subject><subject>Chemotherapy</subject><subject>Comorbidity</subject><subject>Endoscopy</subject><subject>Esophageal cancer</subject><subject>Esophagus</subject><subject>Fistula</subject><subject>Gastroenterology</subject><subject>Gastrointestinal surgery</subject><subject>General Surgery</subject><subject>Hospitals</subject><subject>Length of stay</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Ostomy</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Statistical analysis</subject><subject>Surgical anastomosis</subject><subject>Tomography</subject><subject>Tumors</subject><subject>Veins & arteries</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkc1LJDEQxYO4qLjePEvAyx52ZivpdJI-LTK4HzAysIwnDyGTrp5p6U7apHvB_36j44p6SlHvx0tVPULOGcyVKqtvboo4pbnkFecH5IQzqWeaaXH4pj4mZyndAwADxUHBETkuKhCgNDshd4vgR-yHEG18pH9ChzQ0dDWgp0tsRrreZcUFu6lD33rb0athiMG6HW09vU5h2Nkt5vaN7dqtt9490nVEO_box8_kU2O7hGcv7ym5_XG9XvyaLVc_fy-uljNXAIwzxiotLIJQunJQK16WWmItBXPIsSq1yj1VMiibBqSWdiMKDlCwGgXLYnFKvu99h2nTY-3y19F2Zohtn5cywbbmveLbndmGv4YxLrkClR2-vDjE8DBhGk3fJoddZz2GKZkCdCE1F4pn9PIDeh-mmC_zTEklhVRPhl_3lIshpYjN6zQMzFNyZp-ceU4u4xdvN3iF_-dU_AMlapTe</recordid><startdate>20240622</startdate><enddate>20240622</enddate><creator>Dellaportas, Dionysios</creator><creator>Margaris, Ioannis</creator><creator>Latsonas, Panagiotis</creator><creator>Pikouli, Anastasia</creator><creator>Vlachos, Iakovos</creator><creator>Papakonstantinou, Dimitrios</creator><creator>Pararas, Nikolaos</creator><creator>Nastos, Constantinos</creator><creator>Myoteri, Despoina</creator><creator>Pikoulis, Emmanuel</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240622</creationdate><title>Contemporary Role of Open Left Thoracoabdominal Approach in Esophageal Malignancy Treatment</title><author>Dellaportas, Dionysios ; Margaris, Ioannis ; Latsonas, Panagiotis ; Pikouli, Anastasia ; Vlachos, Iakovos ; Papakonstantinou, Dimitrios ; Pararas, Nikolaos ; Nastos, Constantinos ; Myoteri, Despoina ; Pikoulis, Emmanuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c300t-11984ae04789c0d725586ed641ce2e9587d7275105ff0686ab4320031de4187d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Cancer therapies</topic><topic>Chemotherapy</topic><topic>Comorbidity</topic><topic>Endoscopy</topic><topic>Esophageal cancer</topic><topic>Esophagus</topic><topic>Fistula</topic><topic>Gastroenterology</topic><topic>Gastrointestinal surgery</topic><topic>General Surgery</topic><topic>Hospitals</topic><topic>Length of stay</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Ostomy</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>Statistical analysis</topic><topic>Surgical anastomosis</topic><topic>Tomography</topic><topic>Tumors</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dellaportas, Dionysios</creatorcontrib><creatorcontrib>Margaris, Ioannis</creatorcontrib><creatorcontrib>Latsonas, Panagiotis</creatorcontrib><creatorcontrib>Pikouli, Anastasia</creatorcontrib><creatorcontrib>Vlachos, Iakovos</creatorcontrib><creatorcontrib>Papakonstantinou, Dimitrios</creatorcontrib><creatorcontrib>Pararas, Nikolaos</creatorcontrib><creatorcontrib>Nastos, Constantinos</creatorcontrib><creatorcontrib>Myoteri, Despoina</creatorcontrib><creatorcontrib>Pikoulis, Emmanuel</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dellaportas, Dionysios</au><au>Margaris, Ioannis</au><au>Latsonas, Panagiotis</au><au>Pikouli, Anastasia</au><au>Vlachos, Iakovos</au><au>Papakonstantinou, Dimitrios</au><au>Pararas, Nikolaos</au><au>Nastos, Constantinos</au><au>Myoteri, Despoina</au><au>Pikoulis, Emmanuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contemporary Role of Open Left Thoracoabdominal Approach in Esophageal Malignancy Treatment</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-06-22</date><risdate>2024</risdate><volume>16</volume><issue>6</issue><spage>e62922</spage><pages>e62922-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Despite the widespread use of minimally invasive techniques, open left thoracoabdominal esophagectomy (LTE) can offer excellent visualization and adaptability. The current study aimed to present and evaluate the outcomes related to an open LTE in esophageal malignancy treatment.
A retrospective cohort analysis of data collected from two institutions was performed, including patients with distal esophageal or junctional tumors who underwent open LTE between November 2018 and December 2023.
Twenty-two patients were included (16 males; mean age 62.8 years). Postoperative complications occurred in eight patients (36%), with pulmonary complications being the most prevalent (seven patients; 32%). One patient experienced a clinical anastomotic leak. No reoperations or escalation to a higher level of care were required. In-hospital and 30-day mortality were zero. Tumor cells were found at the surgical margins in six patients (27%). The mean lymph node yield was 27. During the follow-up period, there were nine deaths and 11 cases of disease recurrence. Isolated locoregional recurrence was seen in five patients (23%). The one-year and two-year overall survival rates were 79% and 47%, respectively.
In selected cases, open LTE remains a valid and safe operation with acceptable morbidity and oncological efficacy.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>39040781</pmid><doi>10.7759/cureus.62922</doi><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2024-06, Vol.16 (6), p.e62922 |
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| source | PubMed Central; PubMed Central Open Access |
| subjects | Abdomen Cancer therapies Chemotherapy Comorbidity Endoscopy Esophageal cancer Esophagus Fistula Gastroenterology Gastrointestinal surgery General Surgery Hospitals Length of stay Morbidity Mortality Ostomy Patients Pneumonia Statistical analysis Surgical anastomosis Tomography Tumors Veins & arteries |
| title | Contemporary Role of Open Left Thoracoabdominal Approach in Esophageal Malignancy Treatment |
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