Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS)

[Display omitted] ► We developed an UPLC-ESI/MSMS method to measure 28 urinary VOC metabolites. ► This high throughput method is precise, accurate and sensitive. ► Smokers had higher levels of urinary VOC metabolites compared to non-smokers. ► Serum cotinine correlated well with tobacco related VOC...

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Veröffentlicht in:	Analytica chimica acta 2012-10, Vol.750, p.152-160
Hauptverfasser:	Alwis, K. Udeni, Blount, Benjamin C., Britt, April S., Patel, Dhrusti, Ashley, David L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Applied sciences Biomarkers - urine Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, High Pressure Liquid Chromatography, Reverse-Phase Correlation Cotinine - blood Endogenous Environmental Pollutants - metabolism Environmental Pollutants - urine Exact sciences and technology Global environmental pollution Other chromatographic methods Pollution Smoking Spectrometric and optical methods Spectrometry, Mass, Electrospray Ionization Tobacco-related UPLC-ESI/MSMS Urinary biomarkers VOC metabolites Volatile Organic Compounds - metabolism Volatile Organic Compounds - urine
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