Is serum BDNF level relıable parameter ın detectıng of dental anxıety before ımpacted thırd molar surgery?
Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery. In this randomized, double-bli...
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| Veröffentlicht in: | Medicina oral, patología oral y cirugía bucal patología oral y cirugía bucal, 2024-07, Vol.29 (4), p.e584-e590 |
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| container_title | Medicina oral, patología oral y cirugía bucal |
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| creator | Sıvrıkaya, E-C Yılmaz, O Tuzuner, T Korkmaz, Y-T Alver, A Arıkan, S-M Kocak, N Sahın, E |
| description | Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery.
In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them. |
| doi_str_mv | 10.4317/medoral.26558 |
| format | Article |
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In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them.</description><identifier>ISSN: 1698-6946</identifier><identifier>ISSN: 1698-4447</identifier><identifier>EISSN: 1698-6946</identifier><identifier>DOI: 10.4317/medoral.26558</identifier><identifier>PMID: 38907644</identifier><language>eng</language><publisher>Spain: Medicina Oral S.L</publisher><subject>Adolescent ; Adult ; Brain-Derived Neurotrophic Factor - blood ; Cross-Sectional Studies ; Dental Anxiety - blood ; Double-Blind Method ; Female ; Humans ; Male ; Molar, Third - surgery ; Preoperative Period ; Tooth Extraction ; Tooth, Impacted - blood ; Tooth, Impacted - surgery ; Young Adult</subject><ispartof>Medicina oral, patología oral y cirugía bucal, 2024-07, Vol.29 (4), p.e584-e590</ispartof><rights>Copyright: © 2024 Medicina Oral S.L. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249369/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249369/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38907644$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sıvrıkaya, E-C</creatorcontrib><creatorcontrib>Yılmaz, O</creatorcontrib><creatorcontrib>Tuzuner, T</creatorcontrib><creatorcontrib>Korkmaz, Y-T</creatorcontrib><creatorcontrib>Alver, A</creatorcontrib><creatorcontrib>Arıkan, S-M</creatorcontrib><creatorcontrib>Kocak, N</creatorcontrib><creatorcontrib>Sahın, E</creatorcontrib><title>Is serum BDNF level relıable parameter ın detectıng of dental anxıety before ımpacted thırd molar surgery?</title><title>Medicina oral, patología oral y cirugía bucal</title><addtitle>Med Oral Patol Oral Cir Bucal</addtitle><description>Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery.
In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Brain-Derived Neurotrophic Factor - blood</subject><subject>Cross-Sectional Studies</subject><subject>Dental Anxiety - blood</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Molar, Third - surgery</subject><subject>Preoperative Period</subject><subject>Tooth Extraction</subject><subject>Tooth, Impacted - blood</subject><subject>Tooth, Impacted - surgery</subject><subject>Young Adult</subject><issn>1698-6946</issn><issn>1698-4447</issn><issn>1698-6946</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkc1OxCAUhYnROOPP0q1h6aZaCgW6mvividGNrgmlt-MYWiq0E-ex5h3mwUQdzbjiEL6ce7gHoSOSnjJKxFkDlfPanmY8z-UWGhNeyIQXjG9v6BHaC-EtTakggu-iEZVFKjhjY9TdBxzADw2-uHq8wRbmYLEHu1rq0gLutNcN9ODxatniKirTRzXFro63ttcW6_ZjtYR-gUuonYcINp02PVS4f10tfYUbZ7XHYfBT8IvJAdqptQ1wuD730cvN9fPlXfLwdHt_ef6QGMpYn5QaWEYNyyUXtJaFIWURs5Nag9QVNxkYEMJATdNKUJIXgmSQaWpqWcV_SrqPJj--3VDGHZkYNq5JdX7WaL9QTs_U_5d29qqmbq4IyVhBeREdTtYO3r0PEHrVzIIBa3ULbgiKpnGmJDJnEU1-UONdCB7qvzkkVV81qXVN6rumyB9vhvujf3uhn6tHllM</recordid><startdate>20240701</startdate><enddate>20240701</enddate><creator>Sıvrıkaya, E-C</creator><creator>Yılmaz, O</creator><creator>Tuzuner, T</creator><creator>Korkmaz, Y-T</creator><creator>Alver, A</creator><creator>Arıkan, S-M</creator><creator>Kocak, N</creator><creator>Sahın, E</creator><general>Medicina Oral S.L</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240701</creationdate><title>Is serum BDNF level relıable parameter ın detectıng of dental anxıety before ımpacted thırd molar surgery?</title><author>Sıvrıkaya, E-C ; Yılmaz, O ; Tuzuner, T ; Korkmaz, Y-T ; Alver, A ; Arıkan, S-M ; Kocak, N ; Sahın, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-bae423c458673f89c1b91761fae8ad6c2ece77cef30d73159712e2a3cf8d00383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Brain-Derived Neurotrophic Factor - blood</topic><topic>Cross-Sectional Studies</topic><topic>Dental Anxiety - blood</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Molar, Third - surgery</topic><topic>Preoperative Period</topic><topic>Tooth Extraction</topic><topic>Tooth, Impacted - blood</topic><topic>Tooth, Impacted - surgery</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sıvrıkaya, E-C</creatorcontrib><creatorcontrib>Yılmaz, O</creatorcontrib><creatorcontrib>Tuzuner, T</creatorcontrib><creatorcontrib>Korkmaz, Y-T</creatorcontrib><creatorcontrib>Alver, A</creatorcontrib><creatorcontrib>Arıkan, S-M</creatorcontrib><creatorcontrib>Kocak, N</creatorcontrib><creatorcontrib>Sahın, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicina oral, patología oral y cirugía bucal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sıvrıkaya, E-C</au><au>Yılmaz, O</au><au>Tuzuner, T</au><au>Korkmaz, Y-T</au><au>Alver, A</au><au>Arıkan, S-M</au><au>Kocak, N</au><au>Sahın, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is serum BDNF level relıable parameter ın detectıng of dental anxıety before ımpacted thırd molar surgery?</atitle><jtitle>Medicina oral, patología oral y cirugía bucal</jtitle><addtitle>Med Oral Patol Oral Cir Bucal</addtitle><date>2024-07-01</date><risdate>2024</risdate><volume>29</volume><issue>4</issue><spage>e584</spage><epage>e590</epage><pages>e584-e590</pages><issn>1698-6946</issn><issn>1698-4447</issn><eissn>1698-6946</eissn><abstract>Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery.
In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them.</abstract><cop>Spain</cop><pub>Medicina Oral S.L</pub><pmid>38907644</pmid><doi>10.4317/medoral.26558</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Medicina oral, patología oral y cirugía bucal, 2024-07, Vol.29 (4), p.e584-e590 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Adolescent Adult Brain-Derived Neurotrophic Factor - blood Cross-Sectional Studies Dental Anxiety - blood Double-Blind Method Female Humans Male Molar, Third - surgery Preoperative Period Tooth Extraction Tooth, Impacted - blood Tooth, Impacted - surgery Young Adult |
| title | Is serum BDNF level relıable parameter ın detectıng of dental anxıety before ımpacted thırd molar surgery? |
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