Cell biology of prion strains in vivo and in vitro

The properties of infectious prions and the pathology of the diseases they cause are dependent upon the unique conformation of each prion strain. How the pathology of prion disease correlates with different strains and genetic backgrounds has been investigated via in vivo assays, but how interaction...

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Veröffentlicht in:	Cell and tissue research 2023-04, Vol.392 (1), p.269-283
Hauptverfasser:	Shoup, Daniel, Priola, Suzette A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cell Line Cell lines Cells Conformation Disease Genetic diversity Human Genetics Humans Medical research Medicine, Experimental Molecular Medicine Pathology Persistent infection Phenotypes Prion Diseases - genetics Prion Diseases - metabolism Prion protein Prions Prions - metabolism Proteomics Review
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