Caspase-8 activity mediates TNFα production and restricts Coxiella burnetii replication during murine macrophage infection

is an obligate intracellular bacteria that causes the global zoonotic disease Q Fever. Treatment options for chronic infection are limited, and the development of novel therapeutic strategies requires a greater understanding of how interacts with immune signaling. Cell death responses are known to b...

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Veröffentlicht in:Infection and immunity 2024-07, Vol.92 (7), p.e0005324
Hauptverfasser: Osbron, Chelsea A, Lawson, Crystal, Hanna, Nolan, Koehler, Heather S, Goodman, Alan G
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Sprache:eng
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