Opportunities and Challenges in the Development of Antibody-Drug Conjugate for Triple-Negative Breast Cancer: The Diverse Choices and Changing Needs

Triple-negative breast cancer (TNBC) is a highly heterogeneous breast cancer subtype, which is also characterized by the aggressive phenotype, high recurrence rate, and poor prognosis. Antibody-drug conjugate (ADC) is a monoclonal antibody with a cytotoxic payload connected by a linker. ADC is gaini...

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Veröffentlicht in:	World journal of oncology 2024-08, Vol.15 (4), p.527-542
Hauptverfasser:	Tang, Qi, Li, Hui, Zhao, Xin Tong, Li, Ze Ying, Ma, Chun Xiao, Zhou, Shao Qiang, Chen, De Dian
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
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