Microglial circ-UBE2K exacerbates depression by regulating parental gene UBE2K via targeting HNRNPU

Knowledge about the pathogenesis of depression and treatments for this disease are lacking. Epigenetics-related circRNAs are likely involved in the mechanism of depression and have great potential as treatment targets, but their mechanism of action is still unclear. Circular RNA UBE2K (circ-UBE2K) w...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Theranostics 2024-01, Vol.14 (10), p.4058-4075
Hauptverfasser:	Cai, Yujie, Ji, Yao, Liu, Yingxuan, Zhang, Dandan, Gong, Zheng, Li, Li, Chen, Xiongjin, Liang, Chunmei, Feng, Sifan, Lu, Jiongtong, Qiu, Qinjie, Lin, Zhixiong, Wang, Yan, Cui, Lili
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Depression - genetics Depression - metabolism Depressive Disorder, Major - genetics Depressive Disorder, Major - metabolism Disease Models, Animal Female Hippocampus - metabolism Humans Male Mice Mice, Inbred C57BL Microglia - metabolism Middle Aged Research Paper RNA, Circular - genetics RNA, Circular - metabolism Ubiquitin-Conjugating Enzymes - genetics Ubiquitin-Conjugating Enzymes - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!