PHF2 regulates genome topology and DNA replication in neural stem cells via cohesinlongmeta

Cohesin plays a crucial role in the organization of topologically-associated domains (TADs), which influence gene expression and DNA replication timing. Whether epigenetic regulators may affect TADs via cohesin to mediate DNA replication remains elusive. Here, we discover that the histone demethylas...

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Veröffentlicht in:	Nucleic acids research 2024-05, Vol.52 (12), p.7063-7080
Hauptverfasser:	Feng, Jia, Chuah, You Heng, Liang, Yajing, Cipta, Nadia Omega, Zeng, Yingying, Warrier, Tushar, Elfar, Gamal Ahmed Rashed Elsayed, Yoon, Jeehyun, Grinchuk, Oleg V, Tay, Emmy Xue Yun, Lok, Ker-Zhing, Zheng, Zong-Qing, Khong, Zi Jian, Chong, Zheng-Shan, Teo, Jackie, Sanford, Emma May, Neo, Cheryl Jia Yi, Chiu, Hsin Yao, Leung, Jia Yu, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M, Crasta, Karen Carmelina, Tergaonkar, Vinay, Taneja, Reshma, Ng, Shi-Yan, Cheok, Chit Fang, Ling, Shuo-Chien, Loh, Yuin-Han, Ong, Derrick Sek Tong
Format:	Artikel
Sprache:	eng
Schlagworte:	Genomics
Online-Zugang:	Volltext
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