A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome
Heterotaxy is a syndrome characterized by a spectrum of anatomical anomalies in organ lateralization due to embryological errors. It frequently involves intrathoracic organs, especially the heart, leading to congenital abnormalities. Abdominal organs can also be affected, causing clinical features s...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-07, Vol.16 (7), p.e63664 |
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| creator | Lin, Zhongqian Rahman, Aruni Quintero, Samuel |
| description | Heterotaxy is a syndrome characterized by a spectrum of anatomical anomalies in organ lateralization due to embryological errors. It frequently involves intrathoracic organs, especially the heart, leading to congenital abnormalities. Abdominal organs can also be affected, causing clinical features such as sepsis from asplenia or intestinal volvulus; however, these are less studied. Currently, there is no data on the relationship between heterotaxy and malignancy. We present an interesting case of an elderly adult admitted for a workup of newly diagnosed pancreatic ductal carcinoma, who was found to have heterotaxy of the stomach and spleen, with eventual tumor invasion of these organs. This case suggests that heterotaxy may increase the risk of gastrointestinal malignancy and result in a poorer prognosis due to the complexity of tumor resection involving additional organs. |
| doi_str_mv | 10.7759/cureus.63664 |
| format | Article |
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Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Lin et al. 2024 Lin et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-dc7755dcf028520f000ba5e0518f46aac884489629a3e05a044c6a33d803ebb13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11218713/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11218713/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38957513$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, Zhongqian</creatorcontrib><creatorcontrib>Rahman, Aruni</creatorcontrib><creatorcontrib>Quintero, Samuel</creatorcontrib><title>A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Heterotaxy is a syndrome characterized by a spectrum of anatomical anomalies in organ lateralization due to embryological errors. 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This case suggests that heterotaxy may increase the risk of gastrointestinal malignancy and result in a poorer prognosis due to the complexity of tumor resection involving additional organs.</description><subject>Abdomen</subject><subject>Atrophy</subject><subject>Case reports</subject><subject>Chemotherapy</subject><subject>Congenital diseases</subject><subject>Endoscopy</subject><subject>Gastroenterology</subject><subject>Hospitals</subject><subject>Liver cancer</subject><subject>Medical imaging</subject><subject>Medical screening</subject><subject>Oncology</subject><subject>Pancreatic cancer</subject><subject>Patients</subject><subject>Radiology</subject><subject>Small intestine</subject><subject>Spleen</subject><subject>Stomach</subject><subject>Ultrasonic imaging</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc1r3DAQxUVoaUKaW89B0EsP3XRk2ZJ8Kss2XxBooS05ill5nDjYUirJpfvfR8kmIelphpkfj_d4jH0QcKR1035xc6Q5HSmpVL3D9iqhzMIIU795se-yg5RuAECArkDDO7YrTdvoRsg9drnkK0zEQ89_oHeRMA-Of5tdxpEvO_LBYXSDDxPywXP0_HjsKI6b8pzHzC-HfM3PKFMMGf9t-M-N72KY6D172-OY6OBx7rPfJ8e_VmeLi--n56vlxcJJgLzoXInRdK6HyjQV9MXlGhuCRpi-VojOmLo2rapalOWKUNdOoZSdAUnrtZD77OtW93ZeT9Q58jniaG_jMGHc2ICDff3xw7W9Cn-tEJUwWsii8OlRIYY_M6VspyE5Gkf0FOZkJehGalNpXdCP_6E3YY6-5CuUUUq2Cu4tfd5SLoaUIvXPbgTY-9bstjX70FrBD18meIafOpJ33s6TTQ</recordid><startdate>20240702</startdate><enddate>20240702</enddate><creator>Lin, Zhongqian</creator><creator>Rahman, Aruni</creator><creator>Quintero, Samuel</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240702</creationdate><title>A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome</title><author>Lin, Zhongqian ; 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| subjects | Abdomen Atrophy Case reports Chemotherapy Congenital diseases Endoscopy Gastroenterology Hospitals Liver cancer Medical imaging Medical screening Oncology Pancreatic cancer Patients Radiology Small intestine Spleen Stomach Ultrasonic imaging |
| title | A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome |
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