Mitral regurgitation severity at left ventricular assist device implantation is associated with distinct myocardial transcriptomic signatures

We examined for differences in pre–left ventricular assist device (LVAD) implantation myocardial transcriptome signatures among patients with different degrees of mitral regurgitation (MR). Between January 2018 and October 2019, we collected left ventricular (LV) cores during durable LVAD implantati...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2023-07, Vol.166 (1), p.141-152.e1
Hauptverfasser:	Duggal, Neal M., Lei, Ienglam, Wu, Xiaoting, Aaronson, Keith D., Pagani, Francis D., Lam, Hugo Y.-K., Tang, Paul C., Haft, Jonathan W., Romano, Matthew A., Bolling, Steven F., Abou El Ela, Ashraf, Janda, Allison, Ailawadi, Gorav, Nordsletten, David
Format:	Artikel
Sprache:	eng
Schlagworte:	heart failure Heart Failure - genetics Heart Failure - surgery Heart Transplantation Heart-Assist Devices Humans Inflammation left ventricular assist device mitral regurgitation Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - genetics Mitral Valve Insufficiency - surgery outcomes Retrospective Studies Tissue Donors Transcriptome transcriptomics Treatment Outcome
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