Biocatalytic Stereoselective Oxidation of 2‑Arylindoles

3-Hydroxyindolenines can be used to access several structural motifs that are featured in natural products and pharmaceutical compounds, yet the chemical synthesis of 3-hydroxyindolenines is complicated by overoxidation, rearrangements, and complex product mixtures. The selectivity possible in enzym...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-01, Vol.146 (4), p.2728-2735
Hauptverfasser:	Champagne, Sarah E., Chiang, Chang-Hwa, Gemmel, Philipp M., Narayan, Alison R. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocatalysis Biological Products Catalysis Mixed Function Oxygenases - chemistry Oxidation-Reduction
Online-Zugang:	Volltext
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