Leukemic Stem Cells and Hematological Malignancies

The association between leukemic stem cells (LSCs) and leukemia development has been widely established in the context of genetic alterations, epigenetic pathways, and signaling pathway regulation. Hematopoietic stem cells are at the top of the bone marrow hierarchy and can self-renew and progressiv...

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Veröffentlicht in:	International journal of molecular sciences 2024-06, Vol.25 (12), p.6639
Hauptverfasser:	Choi, Hee-Seon, Kim, Byoung Soo, Yoon, Sik, Oh, Sae-Ock, Lee, Dongjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B cells Blood cancer Bone marrow Cancer Cancer therapies Chemotherapy Chromosomes Cytokines Development and progression Diseases Drug Resistance, Neoplasm - genetics Epigenesis, Genetic Epigenetic inheritance Gene mutations Genetic aspects Health aspects Hematologic Neoplasms - genetics Hematologic Neoplasms - metabolism Hematologic Neoplasms - pathology Hematology Hematopoietic Stem Cells - metabolism Homeostasis Humans Hypoxia Kinases Leukemia Leukemia - genetics Leukemia - metabolism Leukemia - pathology Leukocytes Lymphatic system Lymphocytes Lymphoma Multiple myeloma Mutation Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Relapse Review Signal Transduction Stem cells Tumor Microenvironment - genetics Vincristine
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