Incidence and molecular characteristics of deficient mismatch repair conditions across nine different tumors and identification of germline variants involved in Lynch-like syndrome

Background Based on molecular characteristics, deficient DNA mismatch repair (dMMR) solid tumors are largely divided into three categories: somatically MLH1 -hypermethylated tumors, Lynch syndrome (LS)-associated tumors, and Lynch-like syndrome (LLS)-associated tumors. The incidence of each of these...

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Veröffentlicht in:International journal of clinical oncology 2024-07, Vol.29 (7), p.953-963
Hauptverfasser: Ito, Tetsuya, Yamaguchi, Tatsuro, Kumamoto, Kensuke, Suzuki, Okihide, Chika, Noriyasu, Kawakami, Satoru, Nagai, Tomonori, Igawa, Tsukasa, Fujiyoshi, Kenji, Akagi, Yoshito, Arai, Tomio, Akagi, Kiwamu, Eguchi, Hidetaka, Okazaki, Yasushi, Ishida, Hideyuki
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Sprache:eng
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