Interaction of the C2C12 myotube contractions and glucose availability on transcriptome and extracellular vesicle microRNAs

Exercise-like electrical pulse stimulation (EL-EPS) of myotubes mimics many key physiological changes induced by in vivo exercise. Besides enabling intracellular research, EL-EPS allows to study secreted factors, including muscle-specific microRNAs (myomiRs) carried in extracellular vesicles (EVs)....

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2024-02, Vol.326 (2), p.C348-C361
Hauptverfasser:	Lautaoja-Kivipelto, Juulia H, Karvinen, Sira, Korhonen, Tia-Marje, O'Connell, Thomas M, Tiirola, Marja, Hulmi, Juha J, Pekkala, Satu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytokines - metabolism Electric Stimulation Extracellular Vesicles - genetics Extracellular Vesicles - metabolism Gene expression Glucose Glucose - metabolism Glucose - pharmacology Inflammation Intracellular MicroRNAs MicroRNAs - metabolism miRNA Muscle contraction Muscle Contraction - physiology Muscle Fibers, Skeletal - metabolism Myotubes Transcriptome Transcriptomes
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