The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Outcomes of Acute Organophosphorus Poisoning: A Comprehensive Review
Organophosphorus poisoning (OPP) poses a significant threat to human health, necessitating accurate prognostic markers for timely intervention and improved outcomes. This review evaluates the potential of the neutrophil-to-lymphocyte ratio (NLR) as a prognostic indicator in acute organophosphorus po...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-05, Vol.16 (5), p.e60854 |
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| creator | Pradeep, Utkarsh Chiwhane, Anjalee Acharya, Sourya Kumar, Sunil Daiya, Varun Kasat, Paschyanti R Gupta, Aman Bedi, Gautam N |
| description | Organophosphorus poisoning (OPP) poses a significant threat to human health, necessitating accurate prognostic markers for timely intervention and improved outcomes. This review evaluates the potential of the neutrophil-to-lymphocyte ratio (NLR) as a prognostic indicator in acute organophosphorus poisoning (AOPP). A comprehensive analysis of existing literature reveals that elevated NLR values correlate with increased severity of poisoning and adverse clinical outcomes, including mortality and morbidity. NLR assessment offers valuable prognostic information beyond traditional markers, aiding risk stratification and guiding clinical decision-making. Integration of NLR into clinical practice holds promise for optimizing patient care through the early identification of high-risk individuals and tailored therapeutic interventions. Further research is needed to validate the utility of NLR in larger patient cohorts and standardize its incorporation into clinical guidelines. Leveraging NLR as a prognostic tool can enhance risk stratification, optimize treatment strategies, and ultimately improve outcomes in AOPP. |
| doi_str_mv | 10.7759/cureus.60854 |
| format | Article |
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This review evaluates the potential of the neutrophil-to-lymphocyte ratio (NLR) as a prognostic indicator in acute organophosphorus poisoning (AOPP). A comprehensive analysis of existing literature reveals that elevated NLR values correlate with increased severity of poisoning and adverse clinical outcomes, including mortality and morbidity. NLR assessment offers valuable prognostic information beyond traditional markers, aiding risk stratification and guiding clinical decision-making. Integration of NLR into clinical practice holds promise for optimizing patient care through the early identification of high-risk individuals and tailored therapeutic interventions. Further research is needed to validate the utility of NLR in larger patient cohorts and standardize its incorporation into clinical guidelines. 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Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Pradeep et al. 2024 Pradeep et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-cd296abfe6c43bd2f9a3ca2dcdc44d8962dd0af960c533a81bf6b9a333de3c473</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11191379/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11191379/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38910647$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pradeep, Utkarsh</creatorcontrib><creatorcontrib>Chiwhane, Anjalee</creatorcontrib><creatorcontrib>Acharya, Sourya</creatorcontrib><creatorcontrib>Kumar, Sunil</creatorcontrib><creatorcontrib>Daiya, Varun</creatorcontrib><creatorcontrib>Kasat, Paschyanti R</creatorcontrib><creatorcontrib>Gupta, Aman</creatorcontrib><creatorcontrib>Bedi, Gautam N</creatorcontrib><title>The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Outcomes of Acute Organophosphorus Poisoning: A Comprehensive Review</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Organophosphorus poisoning (OPP) poses a significant threat to human health, necessitating accurate prognostic markers for timely intervention and improved outcomes. 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Leveraging NLR as a prognostic tool can enhance risk stratification, optimize treatment strategies, and ultimately improve outcomes in AOPP.</description><subject>Exercise</subject><subject>Hypertension</subject><subject>Inflammation</subject><subject>Internal Medicine</subject><subject>Lymphocytes</subject><subject>Medical Education</subject><subject>Medical prognosis</subject><subject>Mortality</subject><subject>Nervous system</subject><subject>Neutrophils</subject><subject>Phosphorylation</subject><subject>Physical fitness</subject><subject>Physiology</subject><subject>Poisoning</subject><subject>Toxicity</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpd0c2L1DAYBvAgiruse_MsBS8etmvSpGnrRYbBLxicRdZzSJO30yxtUvMxMgf_dzPOuqweQgL55SEvD0IvCb5umrp7q5KHFK45bmv2BJ1XhLdlS1r29NH5DF2GcIcxJripcIOfozPadgRz1pyjX7cjFN_cBIUbiq-QonfLaKYyunJzmJfRqUPMQEbjCmOLGw_aqGjsrtimqNwM4fhwpVJWW7-TNj93IS-fQnHjTHA243fFqli7efEwgg1mnxNhb-DnC_RskFOAy_v9An3_-OF2_bncbD99Wa82paIYx1LpquOyH4ArRntdDZ2kSlZaacWYbjteaY3l0HGsakplS_qB99lQqoEq1tAL9P6Uu6R-Bq3ARi8nsXgzS38QThrx7401o9i5vSCEdIQ2XU54c5_g3Y8EIYrZBAXTJC24FATFDakJZbTO9PV_9M4lb_N8R0VbzjjBWV2dlPIuBA_Dw28IFsduxalb8afbzF89nuAB_22S_gadt6Qi</recordid><startdate>20240522</startdate><enddate>20240522</enddate><creator>Pradeep, Utkarsh</creator><creator>Chiwhane, Anjalee</creator><creator>Acharya, Sourya</creator><creator>Kumar, Sunil</creator><creator>Daiya, Varun</creator><creator>Kasat, Paschyanti R</creator><creator>Gupta, Aman</creator><creator>Bedi, Gautam N</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240522</creationdate><title>The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Outcomes of Acute Organophosphorus Poisoning: A Comprehensive Review</title><author>Pradeep, Utkarsh ; 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This review evaluates the potential of the neutrophil-to-lymphocyte ratio (NLR) as a prognostic indicator in acute organophosphorus poisoning (AOPP). A comprehensive analysis of existing literature reveals that elevated NLR values correlate with increased severity of poisoning and adverse clinical outcomes, including mortality and morbidity. NLR assessment offers valuable prognostic information beyond traditional markers, aiding risk stratification and guiding clinical decision-making. Integration of NLR into clinical practice holds promise for optimizing patient care through the early identification of high-risk individuals and tailored therapeutic interventions. Further research is needed to validate the utility of NLR in larger patient cohorts and standardize its incorporation into clinical guidelines. 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| subjects | Exercise Hypertension Inflammation Internal Medicine Lymphocytes Medical Education Medical prognosis Mortality Nervous system Neutrophils Phosphorylation Physical fitness Physiology Poisoning Toxicity |
| title | The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Outcomes of Acute Organophosphorus Poisoning: A Comprehensive Review |
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