Isolated Abducens Nerve Palsy: A Rare Manifestation of Recurrent Extramedullary Myeloma
Multiple myeloma is a plasma cell neoplasm, which may present as a solitary plasmacytoma and, uncommonly, as an extramedullary plasmacytoma. Intracranial plasmacytomas may manifest in central nervous system involvement as cranial nerve palsies. Cranial nerve six palsy is the most common in cases of...
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| Veröffentlicht in: | Journal of radiology case reports 2024-01, Vol.18 (1), p.14-19 |
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| container_title | Journal of radiology case reports |
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| creator | Joshi, Neal Li, Joy Karambelkar, Ajit Boere, Payton |
| description | Multiple myeloma is a plasma cell neoplasm, which may present as a solitary plasmacytoma and, uncommonly, as an extramedullary plasmacytoma. Intracranial plasmacytomas may manifest in central nervous system involvement as cranial nerve palsies. Cranial nerve six palsy is the most common in cases of malignancy. However, isolated abducens palsy presenting as multiple myeloma recurrence is very uncommon. Here, we detail two cases in which intracranial plasmacytoma lesions were present within the region of the Dorello canal, resulting in acute isolated unilateral diplopia from disease recurrence in the absence of systemic marrow involvement. |
| doi_str_mv | 10.3941/jrcr.v18i1.5240 |
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Intracranial plasmacytomas may manifest in central nervous system involvement as cranial nerve palsies. Cranial nerve six palsy is the most common in cases of malignancy. However, isolated abducens palsy presenting as multiple myeloma recurrence is very uncommon. Here, we detail two cases in which intracranial plasmacytoma lesions were present within the region of the Dorello canal, resulting in acute isolated unilateral diplopia from disease recurrence in the absence of systemic marrow involvement.</description><identifier>ISSN: 1943-0922</identifier><identifier>EISSN: 1943-0922</identifier><identifier>DOI: 10.3941/jrcr.v18i1.5240</identifier><identifier>PMID: 38910589</identifier><language>eng</language><publisher>United States: EduRad</publisher><subject>Abducens Nerve Diseases - etiology ; Aged ; Brain Neoplasms - complications ; Brain Neoplasms - diagnostic imaging ; Diagnosis, Differential ; Diplopia - etiology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multiple Myeloma - complications ; Multiple Myeloma - diagnostic imaging ; Neoplasm Recurrence, Local ; Neuroimaging ; Plasmacytoma - complications ; Plasmacytoma - diagnostic imaging ; Plasmacytoma - pathology</subject><ispartof>Journal of radiology case reports, 2024-01, Vol.18 (1), p.14-19</ispartof><rights>Copyright Journal of Radiology Case Reports.</rights><rights>Copyright Journal of Radiology Case Reports 2024</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11188768/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11188768/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38910589$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Joshi, Neal</creatorcontrib><creatorcontrib>Li, Joy</creatorcontrib><creatorcontrib>Karambelkar, Ajit</creatorcontrib><creatorcontrib>Boere, Payton</creatorcontrib><title>Isolated Abducens Nerve Palsy: A Rare Manifestation of Recurrent Extramedullary Myeloma</title><title>Journal of radiology case reports</title><addtitle>J Radiol Case Rep</addtitle><description>Multiple myeloma is a plasma cell neoplasm, which may present as a solitary plasmacytoma and, uncommonly, as an extramedullary plasmacytoma. 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Here, we detail two cases in which intracranial plasmacytoma lesions were present within the region of the Dorello canal, resulting in acute isolated unilateral diplopia from disease recurrence in the absence of systemic marrow involvement.</description><subject>Abducens Nerve Diseases - etiology</subject><subject>Aged</subject><subject>Brain Neoplasms - complications</subject><subject>Brain Neoplasms - diagnostic imaging</subject><subject>Diagnosis, Differential</subject><subject>Diplopia - etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multiple Myeloma - complications</subject><subject>Multiple Myeloma - diagnostic imaging</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neuroimaging</subject><subject>Plasmacytoma - complications</subject><subject>Plasmacytoma - diagnostic imaging</subject><subject>Plasmacytoma - pathology</subject><issn>1943-0922</issn><issn>1943-0922</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkcFPwjAUxhujEUXP3kyPXoC-detaL4YQVBJQQzQem248dGSs2m5E_nuLKMFT27yv3_u-_Ai5ANblKobewuWuuwJZQDeJYnZATkDFvMNUFB3u3Vvk1PsFY0KIhB-TFpcKWCLVCXkdeVuaGme0n82aHCtPH9CtkD6Z0q-vaZ9OjUM6MVUxR1-burAVtXM6xbxxDquaDr9qZ5Y4a8rSuDWdrLG0S3NGjubBAc9_zzZ5uR0-D-4748e70aA_7uRRKuuOwMyoGIGpVEWCMyXiLAPFmZB56JdjKiDiWYIzyVUUxzyM0wREYtLwBsPb5Gbr-9FkIUQoENKU-sMVy5BGW1Po_5OqeNdvdqUBQMpUyOBw9evg7GcTOupl4XMMbSq0jdecpZAAV2oj7W2lubPeO5zv9gDTGx56w0P_8NAbHuHH5X68nf4PAP8GZKaH7w</recordid><startdate>20240101</startdate><enddate>20240101</enddate><creator>Joshi, Neal</creator><creator>Li, Joy</creator><creator>Karambelkar, Ajit</creator><creator>Boere, Payton</creator><general>EduRad</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240101</creationdate><title>Isolated Abducens Nerve Palsy: A Rare Manifestation of Recurrent Extramedullary Myeloma</title><author>Joshi, Neal ; Li, Joy ; Karambelkar, Ajit ; Boere, Payton</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c278t-6eba94e109792630964bb193068c941ce76123b5ed83924434bb75165a73921a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abducens Nerve Diseases - etiology</topic><topic>Aged</topic><topic>Brain Neoplasms - complications</topic><topic>Brain Neoplasms - diagnostic imaging</topic><topic>Diagnosis, Differential</topic><topic>Diplopia - etiology</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multiple Myeloma - complications</topic><topic>Multiple Myeloma - diagnostic imaging</topic><topic>Neoplasm Recurrence, Local</topic><topic>Neuroimaging</topic><topic>Plasmacytoma - complications</topic><topic>Plasmacytoma - diagnostic imaging</topic><topic>Plasmacytoma - pathology</topic><toplevel>online_resources</toplevel><creatorcontrib>Joshi, Neal</creatorcontrib><creatorcontrib>Li, Joy</creatorcontrib><creatorcontrib>Karambelkar, Ajit</creatorcontrib><creatorcontrib>Boere, Payton</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of radiology case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Joshi, Neal</au><au>Li, Joy</au><au>Karambelkar, Ajit</au><au>Boere, Payton</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolated Abducens Nerve Palsy: A Rare Manifestation of Recurrent Extramedullary Myeloma</atitle><jtitle>Journal of radiology case reports</jtitle><addtitle>J Radiol Case Rep</addtitle><date>2024-01-01</date><risdate>2024</risdate><volume>18</volume><issue>1</issue><spage>14</spage><epage>19</epage><pages>14-19</pages><issn>1943-0922</issn><eissn>1943-0922</eissn><abstract>Multiple myeloma is a plasma cell neoplasm, which may present as a solitary plasmacytoma and, uncommonly, as an extramedullary plasmacytoma. 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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Abducens Nerve Diseases - etiology Aged Brain Neoplasms - complications Brain Neoplasms - diagnostic imaging Diagnosis, Differential Diplopia - etiology Female Humans Magnetic Resonance Imaging Male Middle Aged Multiple Myeloma - complications Multiple Myeloma - diagnostic imaging Neoplasm Recurrence, Local Neuroimaging Plasmacytoma - complications Plasmacytoma - diagnostic imaging Plasmacytoma - pathology |
| title | Isolated Abducens Nerve Palsy: A Rare Manifestation of Recurrent Extramedullary Myeloma |
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