Human cytomegalovirus seropositivity and its influence on oral rotavirus vaccine immunogenicity: a specific concern for HIV-exposed-uninfected infants

Oral rotavirus vaccines demonstrate diminished immunogenicity in low-income settings where human cytomegalovirus infection is acquired early in childhood and modulates immunity. We hypothesized that human cytomegalovirus infection around the time of vaccination may influence immunogenicity. We measu...

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Veröffentlicht in:Clinical and experimental immunology 2024-06, Vol.217 (1), p.99-108
Hauptverfasser: Laban, Natasha, Bosomprah, Samuel, Chilengi, Roma, Simuyandi, Michelo, Chisenga, Caroline, Ng'ombe, Harriet, Musukuma-Chifulo, Kalo, Goodier, Martin
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Sprache:eng
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