Biotechnological approaches for the production of camptothecin

Camptothecin (CPT), an indole alkaloid popular for its anticancer property, is considered the third most promising drug after taxol and famous alkaloids from Vinca for the treatment of cancer in humans. Camptothecin was first identified in Camptotheca acuminata followed by several other plant specie...

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Veröffentlicht in:	Applied microbiology and biotechnology 2024-12, Vol.108 (1), p.382-382, Article 382
Hauptverfasser:	Banadka, Akshatha, Narasimha, Sudheer Wudali, Dandin, Vijayalaxmi S., Naik, Poornanand M., Vennapusa, Amaranatha Reddy, Melmaiee, Kalpalatha, Vemanna, Ramu S., Al-Khayri, Jameel M., Thiruvengadam, Muthu, Nagella, Praveen
Format:	Artikel
Sprache:	eng
Schlagworte:	adventitious roots Alkaloids Anticancer properties antineoplastic activity Antineoplastic Agents, Phytogenic - biosynthesis biochemical pathways Biomedical and Life Sciences Bioreactors Biotechnology Biotechnology - methods Callus Callus culture Camptotheca - metabolism Camptotheca acuminata Camptothecin Camptothecin - biosynthesis Cancer Cell culture cell suspension culture cost effectiveness Culture techniques DNA topoisomerase drugs Endophytes Endophytes - genetics Endophytes - metabolism Fungi genes genetic engineering Genetic modification Genome editing Genotypes Hairy root Humans indole alkaloids Life Sciences Medical treatment Microbial Genetics and Genomics Microbiology Mini-Review Organ culture Paclitaxel Plant species Plant tissues species Suspension culture Sustainable production Tissue culture Vinca
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