Stewardship Prompts to Improve Antibiotic Selection for Pneumonia: The INSPIRE Randomized Clinical Trial

IMPORTANCE: Pneumonia is the most common infection requiring hospitalization and is a major reason for overuse of extended-spectrum antibiotics. Despite low risk of multidrug-resistant organism (MDRO) infection, clinical uncertainty often drives initial antibiotic selection. Strategies to limit empi...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2024-06, Vol.331 (23), p.2007-2017
Hauptverfasser:	Gohil, Shruti K, Septimus, Edward, Kleinman, Ken, Varma, Neha, Avery, Taliser R, Heim, Lauren, Rahm, Risa, Cooper, William S, Cooper, Mandelin, McLean, Laura E, Nickolay, Naoise G, Weinstein, Robert A, Burgess, L. Hayley, Coady, Micaela H, Rosen, Edward, Sljivo, Selsebil, Sands, Kenneth E, Moody, Julia, Vigeant, Justin, Rashid, Syma, Gilbert, Rebecca F, Smith, Kim N, Carver, Brandon, Poland, Russell E, Hickok, Jason, Sturdevant, S. G, Calderwood, Michael S, Weiland, Anastasiia, Kubiak, David W, Reddy, Sujan, Neuhauser, Melinda M, Srinivasan, Arjun, Jernigan, John A, Hayden, Mary K, Gowda, Abinav, Eibensteiner, Katyuska, Wolf, Robert, Perlin, Jonathan B, Platt, Richard, Huang, Susan S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use Antibiotics Antimicrobial Stewardship Comorbidity Drug Resistance, Multiple, Bacterial Education Feedback Female Health risks Hospitalization Hospitals Humans Infections Intervention Length of stay Male Medical Order Entry Systems Middle Aged Multidrug resistance Multidrug resistant organisms Online First Original Investigation Patients Pneumonia Pneumonia - drug therapy Pneumonia, Bacterial - drug therapy Real time Risk Therapy United States Vancomycin
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