Recommendations for the use of antiretroviral therapy in adults living with human immunodeficiency virus in Singapore
Since the advent of combination antiretroviral therapy (ART), the mortality attributable to human immunodeficiency virus (HIV) infection has decreased by 80%. Newer antiretroviral agents are highly efficacious, have minimal side effects as compared to older drugs, and can be formulated as combinatio...
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| Veröffentlicht in: | Singapore medical journal 2024-05, Vol.65 (5), p.259-273 |
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| container_end_page | 273 |
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| container_issue | 5 |
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| container_title | Singapore medical journal |
| container_volume | 65 |
| creator | Choy, Chiaw Yee Wong, Chen Seong Kumar, P Arun Olszyna, Dariusz Piotr Teh, Yii Ean Chien, Mei Fong Jaime Kurup, Asok Koh, Yin Ling Ho, Lai Peng Law, Hwa Lin Chua, Nathalie Grace Sy Yong, Hui Yan Joy Archuleta, Sophia |
| description | Since the advent of combination antiretroviral therapy (ART), the mortality attributable to human immunodeficiency virus (HIV) infection has decreased by 80%. Newer antiretroviral agents are highly efficacious, have minimal side effects as compared to older drugs, and can be formulated as combination tablets to reduce patients' pill burden. Despite these advances, 680,000 people worldwide died of acquired immunodeficiency syndrome-related illnesses in 2020. The National ART and Monitoring Recommendations by the National HIV Programme have been created to guide physicians on the prescribing of ART based on the patients' needs. These recommendations are based on international guidelines and tailored to the local context and unique domestic considerations. We hoped that with the publication of these recommendations, the care of people living with HIV can be enhanced, bringing us closer to ending HIV in our lifetime. |
| doi_str_mv | 10.11622/smedj.2021174 |
| format | Article |
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Newer antiretroviral agents are highly efficacious, have minimal side effects as compared to older drugs, and can be formulated as combination tablets to reduce patients' pill burden. Despite these advances, 680,000 people worldwide died of acquired immunodeficiency syndrome-related illnesses in 2020. The National ART and Monitoring Recommendations by the National HIV Programme have been created to guide physicians on the prescribing of ART based on the patients' needs. These recommendations are based on international guidelines and tailored to the local context and unique domestic considerations. We hoped that with the publication of these recommendations, the care of people living with HIV can be enhanced, bringing us closer to ending HIV in our lifetime.</description><identifier>ISSN: 0037-5675</identifier><identifier>EISSN: 2737-5935</identifier><identifier>DOI: 10.11622/smedj.2021174</identifier><identifier>PMID: 35366662</identifier><language>eng</language><publisher>India: Wolters Kluwer - Medknow</publisher><subject>Adult ; Anti-HIV Agents - therapeutic use ; Anti-Retroviral Agents - therapeutic use ; Antiretroviral Therapy, Highly Active ; HIV Infections - drug therapy ; Humans ; Male ; Practice Guidelines as Topic ; Review ; Singapore - epidemiology</subject><ispartof>Singapore medical journal, 2024-05, Vol.65 (5), p.259-273</ispartof><rights>Copyright © 2024 Copyright: © 2024 Singapore Medical Journal.</rights><rights>Copyright: © 2024 Singapore Medical Journal 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3025-e654d3fff68a8b625162f17212a9624259adc436e4e61e9f09df0b39daed93553</citedby><cites>FETCH-LOGICAL-c3025-e654d3fff68a8b625162f17212a9624259adc436e4e61e9f09df0b39daed93553</cites><orcidid>0000-0003-4585-2867</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182460/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182460/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35366662$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choy, Chiaw Yee</creatorcontrib><creatorcontrib>Wong, Chen Seong</creatorcontrib><creatorcontrib>Kumar, P Arun</creatorcontrib><creatorcontrib>Olszyna, Dariusz Piotr</creatorcontrib><creatorcontrib>Teh, Yii Ean</creatorcontrib><creatorcontrib>Chien, Mei Fong Jaime</creatorcontrib><creatorcontrib>Kurup, Asok</creatorcontrib><creatorcontrib>Koh, Yin Ling</creatorcontrib><creatorcontrib>Ho, Lai Peng</creatorcontrib><creatorcontrib>Law, Hwa Lin</creatorcontrib><creatorcontrib>Chua, Nathalie Grace Sy</creatorcontrib><creatorcontrib>Yong, Hui Yan Joy</creatorcontrib><creatorcontrib>Archuleta, Sophia</creatorcontrib><title>Recommendations for the use of antiretroviral therapy in adults living with human immunodeficiency virus in Singapore</title><title>Singapore medical journal</title><addtitle>Singapore Med J</addtitle><description>Since the advent of combination antiretroviral therapy (ART), the mortality attributable to human immunodeficiency virus (HIV) infection has decreased by 80%. Newer antiretroviral agents are highly efficacious, have minimal side effects as compared to older drugs, and can be formulated as combination tablets to reduce patients' pill burden. Despite these advances, 680,000 people worldwide died of acquired immunodeficiency syndrome-related illnesses in 2020. The National ART and Monitoring Recommendations by the National HIV Programme have been created to guide physicians on the prescribing of ART based on the patients' needs. These recommendations are based on international guidelines and tailored to the local context and unique domestic considerations. We hoped that with the publication of these recommendations, the care of people living with HIV can be enhanced, bringing us closer to ending HIV in our lifetime.</description><subject>Adult</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Anti-Retroviral Agents - therapeutic use</subject><subject>Antiretroviral Therapy, Highly Active</subject><subject>HIV Infections - drug therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Practice Guidelines as Topic</subject><subject>Review</subject><subject>Singapore - epidemiology</subject><issn>0037-5675</issn><issn>2737-5935</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUdtKAzEQDaLYWn31UfIDW3PZZHefRIo3EAQvz0u6mbQp3aQku5X-venFovMyA2fOGeYchK4pGVMqGbuNLejFmBFGaZGfoCEreJGJiotTNCRkO8tCDNBFjAtCWEHK8hwNuOAyFRui_h0a37bgtOqsdxEbH3A3B9xHwN5g5ToboAt-bYNabpGgVhtsHVa6X3YRL-3auhn-tt0cz_tWOWzbtndeg7GNBddscKL2cUv5SJtq5QNcojOjlhGuDn2Evh4fPifP2evb08vk_jVrOGEiAylyzY0xslTlVDKRPja0YJSpSrKciUrpJucScpAUKkMqbciUV1qBTg4IPkJ3e91VP00-NeC69EW9CrZVYVN7Zev_iLPzeubXNaW0ZLkkSWG8V2iCjzGAOZIpqXcJ1LsE6kMCiXDz9-Rx_ddy_gPwQIaq</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Choy, Chiaw Yee</creator><creator>Wong, Chen Seong</creator><creator>Kumar, P Arun</creator><creator>Olszyna, Dariusz Piotr</creator><creator>Teh, Yii Ean</creator><creator>Chien, Mei Fong Jaime</creator><creator>Kurup, Asok</creator><creator>Koh, Yin Ling</creator><creator>Ho, Lai Peng</creator><creator>Law, Hwa Lin</creator><creator>Chua, Nathalie Grace Sy</creator><creator>Yong, Hui Yan Joy</creator><creator>Archuleta, Sophia</creator><general>Wolters Kluwer - Medknow</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4585-2867</orcidid></search><sort><creationdate>20240501</creationdate><title>Recommendations for the use of antiretroviral therapy in adults living with human immunodeficiency virus in Singapore</title><author>Choy, Chiaw Yee ; 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| ispartof | Singapore medical journal, 2024-05, Vol.65 (5), p.259-273 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Anti-HIV Agents - therapeutic use Anti-Retroviral Agents - therapeutic use Antiretroviral Therapy, Highly Active HIV Infections - drug therapy Humans Male Practice Guidelines as Topic Review Singapore - epidemiology |
| title | Recommendations for the use of antiretroviral therapy in adults living with human immunodeficiency virus in Singapore |
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