Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract
, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytoc...
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Veröffentlicht in: | Journal of pharmacy & bioallied science 2024-04, Vol.16 (Suppl 2), p.S1312-S1316 |
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creator | Nithin Krishna, K Krishnamoorthy, Kalaiselvi Veeraraghavan, Vishnu Priya Jayaraman, Selvaraj |
description | , a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from
.
Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through
assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species.
Phytochemical screening revealed the presence of various bioactive constituents in the
ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress.
The findings of this study underscore the potential of
ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of
. |
doi_str_mv | 10.4103/jpbs.jpbs_596_23 |
format | Article |
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.
Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through
assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species.
Phytochemical screening revealed the presence of various bioactive constituents in the
ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress.
The findings of this study underscore the potential of
ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of
.</description><identifier>ISSN: 0976-4879</identifier><identifier>EISSN: 0975-7406</identifier><identifier>DOI: 10.4103/jpbs.jpbs_596_23</identifier><identifier>PMID: 38882845</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Analysis ; Anti-inflammatory agents ; Anti-inflammatory drugs ; Antioxidants ; Bioactive compounds ; Biological activity ; Chemical composition ; Free radicals ; Health aspects ; India ; Inflammation ; Medicinal plants ; Medicine, Botanic ; Medicine, Herbal ; Natural products ; Natural resources ; Original ; Oxidants ; Oxidative stress ; Phytochemicals ; Plant extracts ; Reactive oxygen species ; Spermacoce hispida ; Therapeutic applications</subject><ispartof>Journal of pharmacy & bioallied science, 2024-04, Vol.16 (Suppl 2), p.S1312-S1316</ispartof><rights>Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.</rights><rights>COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd.</rights><rights>2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c445t-accd4c6ae47a4536ce9a38f943c85d568fca799be48967a91c23403f3c643d163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11174334/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11174334/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38882845$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nithin Krishna, K</creatorcontrib><creatorcontrib>Krishnamoorthy, Kalaiselvi</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><title>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</title><title>Journal of pharmacy & bioallied science</title><addtitle>J Pharm Bioallied Sci</addtitle><description>, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from
.
Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through
assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species.
Phytochemical screening revealed the presence of various bioactive constituents in the
ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress.
The findings of this study underscore the potential of
ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of
.</description><subject>Analysis</subject><subject>Anti-inflammatory agents</subject><subject>Anti-inflammatory drugs</subject><subject>Antioxidants</subject><subject>Bioactive compounds</subject><subject>Biological activity</subject><subject>Chemical composition</subject><subject>Free radicals</subject><subject>Health aspects</subject><subject>India</subject><subject>Inflammation</subject><subject>Medicinal plants</subject><subject>Medicine, Botanic</subject><subject>Medicine, Herbal</subject><subject>Natural products</subject><subject>Natural resources</subject><subject>Original</subject><subject>Oxidants</subject><subject>Oxidative stress</subject><subject>Phytochemicals</subject><subject>Plant extracts</subject><subject>Reactive oxygen species</subject><subject>Spermacoce hispida</subject><subject>Therapeutic applications</subject><issn>0976-4879</issn><issn>0975-7406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNptUl1rHCEUHUpLE9K896kIfenLbHT9GH0qS9g2gUAKaZ_FvePsuszoRN2Q_fdxknSblCh45XrO0Xs9VfWZ4BkjmJ5tx1WaTYvmSug5fVcdY9XwumFYvH_ci5rJRh1VpyltcRlUzRWhH6sjKqWcS8aPq9tfm30OsLGDA9OjG4jWeufXyPgWLXx29aXvejMMJoe4_5e9vnet8RktILs7l51NKHToZrRxMBDAoguXxgJBy7wxPvQO0PI-RwP5U_WhM32yp8_xpPrzY_n7_KK-uv55eb64qoExnmsD0DIQxrLGME4FWGWo7BSjIHnLhezANEqtLJNKNEYRmFOGaUdBMNoSQU-q70-642412BasL9f3eoxuMHGvg3H69Yl3G70Od5oQ0jBKWVH49qwQw-3OpqwHl8D2vfE27JKmWCjScExIgX79D7oNu-hLfZoWvfJGUoo4oNamt9r5LkwdmUT1QhLOJaFq0pq9gSqznT4peNu5kn9FwE8EiCGlaLtDkQTrySr60SUvrFIoX14250D4awz6ABMjvLk</recordid><startdate>202404</startdate><enddate>202404</enddate><creator>Nithin Krishna, K</creator><creator>Krishnamoorthy, Kalaiselvi</creator><creator>Veeraraghavan, Vishnu Priya</creator><creator>Jayaraman, Selvaraj</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202404</creationdate><title>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</title><author>Nithin Krishna, K ; Krishnamoorthy, Kalaiselvi ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-accd4c6ae47a4536ce9a38f943c85d568fca799be48967a91c23403f3c643d163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Analysis</topic><topic>Anti-inflammatory agents</topic><topic>Anti-inflammatory drugs</topic><topic>Antioxidants</topic><topic>Bioactive compounds</topic><topic>Biological activity</topic><topic>Chemical composition</topic><topic>Free radicals</topic><topic>Health aspects</topic><topic>India</topic><topic>Inflammation</topic><topic>Medicinal plants</topic><topic>Medicine, Botanic</topic><topic>Medicine, Herbal</topic><topic>Natural products</topic><topic>Natural resources</topic><topic>Original</topic><topic>Oxidants</topic><topic>Oxidative stress</topic><topic>Phytochemicals</topic><topic>Plant extracts</topic><topic>Reactive oxygen species</topic><topic>Spermacoce hispida</topic><topic>Therapeutic applications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nithin Krishna, K</creatorcontrib><creatorcontrib>Krishnamoorthy, Kalaiselvi</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of pharmacy & bioallied science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nithin Krishna, K</au><au>Krishnamoorthy, Kalaiselvi</au><au>Veeraraghavan, Vishnu Priya</au><au>Jayaraman, Selvaraj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</atitle><jtitle>Journal of pharmacy & bioallied science</jtitle><addtitle>J Pharm Bioallied Sci</addtitle><date>2024-04</date><risdate>2024</risdate><volume>16</volume><issue>Suppl 2</issue><spage>S1312</spage><epage>S1316</epage><pages>S1312-S1316</pages><issn>0976-4879</issn><eissn>0975-7406</eissn><abstract>, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from
.
Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through
assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species.
Phytochemical screening revealed the presence of various bioactive constituents in the
ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress.
The findings of this study underscore the potential of
ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of
.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>38882845</pmid><doi>10.4103/jpbs.jpbs_596_23</doi><oa>free_for_read</oa></addata></record> |
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subjects | Analysis Anti-inflammatory agents Anti-inflammatory drugs Antioxidants Bioactive compounds Biological activity Chemical composition Free radicals Health aspects India Inflammation Medicinal plants Medicine, Botanic Medicine, Herbal Natural products Natural resources Original Oxidants Oxidative stress Phytochemicals Plant extracts Reactive oxygen species Spermacoce hispida Therapeutic applications |
title | Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract |
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