Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract

, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytoc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of pharmacy & bioallied science 2024-04, Vol.16 (Suppl 2), p.S1312-S1316
Hauptverfasser: Nithin Krishna, K, Krishnamoorthy, Kalaiselvi, Veeraraghavan, Vishnu Priya, Jayaraman, Selvaraj
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page S1316
container_issue Suppl 2
container_start_page S1312
container_title Journal of pharmacy & bioallied science
container_volume 16
creator Nithin Krishna, K
Krishnamoorthy, Kalaiselvi
Veeraraghavan, Vishnu Priya
Jayaraman, Selvaraj
description , a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species. Phytochemical screening revealed the presence of various bioactive constituents in the ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress. The findings of this study underscore the potential of ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of .
doi_str_mv 10.4103/jpbs.jpbs_596_23
format Article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11174334</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A815581391</galeid><sourcerecordid>A815581391</sourcerecordid><originalsourceid>FETCH-LOGICAL-c445t-accd4c6ae47a4536ce9a38f943c85d568fca799be48967a91c23403f3c643d163</originalsourceid><addsrcrecordid>eNptUl1rHCEUHUpLE9K896kIfenLbHT9GH0qS9g2gUAKaZ_FvePsuszoRN2Q_fdxknSblCh45XrO0Xs9VfWZ4BkjmJ5tx1WaTYvmSug5fVcdY9XwumFYvH_ci5rJRh1VpyltcRlUzRWhH6sjKqWcS8aPq9tfm30OsLGDA9OjG4jWeufXyPgWLXx29aXvejMMJoe4_5e9vnet8RktILs7l51NKHToZrRxMBDAoguXxgJBy7wxPvQO0PI-RwP5U_WhM32yp8_xpPrzY_n7_KK-uv55eb64qoExnmsD0DIQxrLGME4FWGWo7BSjIHnLhezANEqtLJNKNEYRmFOGaUdBMNoSQU-q70-642412BasL9f3eoxuMHGvg3H69Yl3G70Od5oQ0jBKWVH49qwQw-3OpqwHl8D2vfE27JKmWCjScExIgX79D7oNu-hLfZoWvfJGUoo4oNamt9r5LkwdmUT1QhLOJaFq0pq9gSqznT4peNu5kn9FwE8EiCGlaLtDkQTrySr60SUvrFIoX14250D4awz6ABMjvLk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3111489145</pqid></control><display><type>article</type><title>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Medknow Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Nithin Krishna, K ; Krishnamoorthy, Kalaiselvi ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</creator><creatorcontrib>Nithin Krishna, K ; Krishnamoorthy, Kalaiselvi ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</creatorcontrib><description>, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species. Phytochemical screening revealed the presence of various bioactive constituents in the ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress. The findings of this study underscore the potential of ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of .</description><identifier>ISSN: 0976-4879</identifier><identifier>EISSN: 0975-7406</identifier><identifier>DOI: 10.4103/jpbs.jpbs_596_23</identifier><identifier>PMID: 38882845</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Analysis ; Anti-inflammatory agents ; Anti-inflammatory drugs ; Antioxidants ; Bioactive compounds ; Biological activity ; Chemical composition ; Free radicals ; Health aspects ; India ; Inflammation ; Medicinal plants ; Medicine, Botanic ; Medicine, Herbal ; Natural products ; Natural resources ; Original ; Oxidants ; Oxidative stress ; Phytochemicals ; Plant extracts ; Reactive oxygen species ; Spermacoce hispida ; Therapeutic applications</subject><ispartof>Journal of pharmacy &amp; bioallied science, 2024-04, Vol.16 (Suppl 2), p.S1312-S1316</ispartof><rights>Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.</rights><rights>COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd.</rights><rights>2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c445t-accd4c6ae47a4536ce9a38f943c85d568fca799be48967a91c23403f3c643d163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11174334/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11174334/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38882845$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nithin Krishna, K</creatorcontrib><creatorcontrib>Krishnamoorthy, Kalaiselvi</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><title>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</title><title>Journal of pharmacy &amp; bioallied science</title><addtitle>J Pharm Bioallied Sci</addtitle><description>, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species. Phytochemical screening revealed the presence of various bioactive constituents in the ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress. The findings of this study underscore the potential of ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of .</description><subject>Analysis</subject><subject>Anti-inflammatory agents</subject><subject>Anti-inflammatory drugs</subject><subject>Antioxidants</subject><subject>Bioactive compounds</subject><subject>Biological activity</subject><subject>Chemical composition</subject><subject>Free radicals</subject><subject>Health aspects</subject><subject>India</subject><subject>Inflammation</subject><subject>Medicinal plants</subject><subject>Medicine, Botanic</subject><subject>Medicine, Herbal</subject><subject>Natural products</subject><subject>Natural resources</subject><subject>Original</subject><subject>Oxidants</subject><subject>Oxidative stress</subject><subject>Phytochemicals</subject><subject>Plant extracts</subject><subject>Reactive oxygen species</subject><subject>Spermacoce hispida</subject><subject>Therapeutic applications</subject><issn>0976-4879</issn><issn>0975-7406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNptUl1rHCEUHUpLE9K896kIfenLbHT9GH0qS9g2gUAKaZ_FvePsuszoRN2Q_fdxknSblCh45XrO0Xs9VfWZ4BkjmJ5tx1WaTYvmSug5fVcdY9XwumFYvH_ci5rJRh1VpyltcRlUzRWhH6sjKqWcS8aPq9tfm30OsLGDA9OjG4jWeufXyPgWLXx29aXvejMMJoe4_5e9vnet8RktILs7l51NKHToZrRxMBDAoguXxgJBy7wxPvQO0PI-RwP5U_WhM32yp8_xpPrzY_n7_KK-uv55eb64qoExnmsD0DIQxrLGME4FWGWo7BSjIHnLhezANEqtLJNKNEYRmFOGaUdBMNoSQU-q70-642412BasL9f3eoxuMHGvg3H69Yl3G70Od5oQ0jBKWVH49qwQw-3OpqwHl8D2vfE27JKmWCjScExIgX79D7oNu-hLfZoWvfJGUoo4oNamt9r5LkwdmUT1QhLOJaFq0pq9gSqznT4peNu5kn9FwE8EiCGlaLtDkQTrySr60SUvrFIoX14250D4awz6ABMjvLk</recordid><startdate>202404</startdate><enddate>202404</enddate><creator>Nithin Krishna, K</creator><creator>Krishnamoorthy, Kalaiselvi</creator><creator>Veeraraghavan, Vishnu Priya</creator><creator>Jayaraman, Selvaraj</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202404</creationdate><title>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</title><author>Nithin Krishna, K ; Krishnamoorthy, Kalaiselvi ; Veeraraghavan, Vishnu Priya ; Jayaraman, Selvaraj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-accd4c6ae47a4536ce9a38f943c85d568fca799be48967a91c23403f3c643d163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Analysis</topic><topic>Anti-inflammatory agents</topic><topic>Anti-inflammatory drugs</topic><topic>Antioxidants</topic><topic>Bioactive compounds</topic><topic>Biological activity</topic><topic>Chemical composition</topic><topic>Free radicals</topic><topic>Health aspects</topic><topic>India</topic><topic>Inflammation</topic><topic>Medicinal plants</topic><topic>Medicine, Botanic</topic><topic>Medicine, Herbal</topic><topic>Natural products</topic><topic>Natural resources</topic><topic>Original</topic><topic>Oxidants</topic><topic>Oxidative stress</topic><topic>Phytochemicals</topic><topic>Plant extracts</topic><topic>Reactive oxygen species</topic><topic>Spermacoce hispida</topic><topic>Therapeutic applications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nithin Krishna, K</creatorcontrib><creatorcontrib>Krishnamoorthy, Kalaiselvi</creatorcontrib><creatorcontrib>Veeraraghavan, Vishnu Priya</creatorcontrib><creatorcontrib>Jayaraman, Selvaraj</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of pharmacy &amp; bioallied science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nithin Krishna, K</au><au>Krishnamoorthy, Kalaiselvi</au><au>Veeraraghavan, Vishnu Priya</au><au>Jayaraman, Selvaraj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract</atitle><jtitle>Journal of pharmacy &amp; bioallied science</jtitle><addtitle>J Pharm Bioallied Sci</addtitle><date>2024-04</date><risdate>2024</risdate><volume>16</volume><issue>Suppl 2</issue><spage>S1312</spage><epage>S1316</epage><pages>S1312-S1316</pages><issn>0976-4879</issn><eissn>0975-7406</eissn><abstract>, a medicinal plant from the Rubiaceae family, has garnered attention for its traditional use and reported therapeutic properties. This study aimed to investigate the phytochemical composition and assess the anti-inflammatory and anti-oxidant activities of the ethanolic extract derived from . Phytochemical screening of the ethanolic extract involved qualitative analysis to identify major phytoconstituents such as tannins, phenols, and acids. The anti-inflammatory activity was evaluated through assays, and anti-oxidant potential was assessed using established methods to measure scavenging activity against free radicals and reactive oxygen species. Phytochemical screening revealed the presence of various bioactive constituents in the ethanolic extract, including acid, tannin, protein, and phenolic compounds. Furthermore, the extract exhibited potent anti-oxidant activity, as evidenced by its ability to scavenge free radicals and attenuate ROS-induced oxidative stress. The findings of this study underscore the potential of ethanolic extract as a source of bioactive compounds with anti-inflammatory and anti-oxidant properties. The presence of phytochemicals and the observed bioactivity support its traditional use and suggest potential therapeutic applications. These results contribute to the growing body of knowledge on natural products with health-promoting effects and provide a basis for further research aimed at developing pharmaceutical and medicinal interventions harnessing the benefits of .</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>38882845</pmid><doi>10.4103/jpbs.jpbs_596_23</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0976-4879
ispartof Journal of pharmacy & bioallied science, 2024-04, Vol.16 (Suppl 2), p.S1312-S1316
issn 0976-4879
0975-7406
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11174334
source DOAJ Directory of Open Access Journals; PubMed Central Open Access; Medknow Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Analysis
Anti-inflammatory agents
Anti-inflammatory drugs
Antioxidants
Bioactive compounds
Biological activity
Chemical composition
Free radicals
Health aspects
India
Inflammation
Medicinal plants
Medicine, Botanic
Medicine, Herbal
Natural products
Natural resources
Original
Oxidants
Oxidative stress
Phytochemicals
Plant extracts
Reactive oxygen species
Spermacoce hispida
Therapeutic applications
title Phytochemical Screening and Anti-Inflammatory and Anti-Oxidant Activities of Spermacoce Hispida Ethanolic Extract
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T19%3A14%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Phytochemical%20Screening%20and%20Anti-Inflammatory%20and%20Anti-Oxidant%20Activities%20of%20Spermacoce%20Hispida%20Ethanolic%20Extract&rft.jtitle=Journal%20of%20pharmacy%20&%20bioallied%20science&rft.au=Nithin%20Krishna,%20K&rft.date=2024-04&rft.volume=16&rft.issue=Suppl%202&rft.spage=S1312&rft.epage=S1316&rft.pages=S1312-S1316&rft.issn=0976-4879&rft.eissn=0975-7406&rft_id=info:doi/10.4103/jpbs.jpbs_596_23&rft_dat=%3Cgale_pubme%3EA815581391%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3111489145&rft_id=info:pmid/38882845&rft_galeid=A815581391&rfr_iscdi=true