Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sex

Maternal exposure to environmental chemicals can cause adverse health effects in offspring. Mounting evidence supports that these effects are influenced, at least in part, by epigenetic modifications. It is unknown whether epigenetic changes in surrogate tissues such as the blood are reflective of s...

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Veröffentlicht in:	Environmental health perspectives 2024-06, Vol.132 (6), p.67003
Hauptverfasser:	Morgan, Rachel K, Wang, Kai, Svoboda, Laurie K, Rygiel, Christine A, Lalancette, Claudia, Cavalcante, Raymond, Bartolomei, Marisa S, Prasasya, Rexxi, Neier, Kari, Perera, Bambarendage P U, Jones, Tamara R, Colacino, Justin A, Sartor, Maureen A, Dolinoy, Dana C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Diethylhexyl Phthalate - toxicity DNA Methylation - drug effects Environmental Pollutants - toxicity Epigenesis, Genetic - drug effects Female Genomic Imprinting - drug effects Lead - blood Lead - toxicity Liver - drug effects Male Maternal Exposure Mice Phthalic Acids - toxicity Pregnancy Prenatal Exposure Delayed Effects
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