An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report
Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive im...
Gespeichert in:
Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-05, Vol.16 (5), p.e60146 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 5 |
container_start_page | e60146 |
container_title | Curēus (Palo Alto, CA) |
container_volume | 16 |
creator | Gopal, Kalashree Howard, Jeremiah Ramaraj, Shyamalee Shroff, Ahaj H Gamard, Christopher |
description | Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course. |
doi_str_mv | 10.7759/cureus.60146 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11166250</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3067914947</sourcerecordid><originalsourceid>FETCH-LOGICAL-c300t-df939576e4ec04c9ac131a43f08e0d3ca1d58dbf1fb07fffb854991ec75c07563</originalsourceid><addsrcrecordid>eNpdkc1LXDEUxYNUVNSdawm46cKnN5O8fHRThkFtQTul1EVXIZN3U5-8ScbkpdD_vq8dK7are-H-OJxzDyEnDC6Uas2lrxlruZDAhNwhBzMmdaOZFm9e7fvkuJRHAGCgZqBgj-xzraUAzg_Ich7pfayluoF-zlgwjm7sU6Qp0E9Ycyou-9R3qfSF9pE6KkXzDV1ulkNH71x8R-d04QrSL7hJeTwiu8ENBY-f5yG5v776uvjQ3C5vPi7mt43nAGPTBcNNqyQK9CC8cZ5x5gQPoBE67h3rWt2tAgsrUCGElW6FMQy9aj2oVvJD8n6ru6mrNXZ-8p3dYDe5X7v80ybX238vsX-w39MPyxiTctbCpPD2WSGnp4pltOu-eBwGFzHVYjlIZZgwQk3o2X_oY6o5TvkmSnHNW6P4RJ1vKT99rWQML24Y2N9t2W1b9k9bE376OsEL_Lcb_gugIpBt</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3073835973</pqid></control><display><type>article</type><title>An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Gopal, Kalashree ; Howard, Jeremiah ; Ramaraj, Shyamalee ; Shroff, Ahaj H ; Gamard, Christopher</creator><creatorcontrib>Gopal, Kalashree ; Howard, Jeremiah ; Ramaraj, Shyamalee ; Shroff, Ahaj H ; Gamard, Christopher</creatorcontrib><description>Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.60146</identifier><identifier>PMID: 38864033</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Antigens ; Bronchoscopy ; Case reports ; Cognitive ability ; Diplopia ; Dysphagia ; Dyspnea ; Esophagus ; Eye examinations ; Gastroenterology ; Granulomas ; Hospitalization ; Hyponatremia ; Insomnia ; Leukocytes ; Lymphatic system ; Lymphoma ; Magnetic resonance imaging ; Neurology ; Patients ; Peripheral neuropathy ; Primary care ; Pulmonology ; Sarcoidosis ; Steroids ; Tomography</subject><ispartof>Curēus (Palo Alto, CA), 2024-05, Vol.16 (5), p.e60146</ispartof><rights>Copyright © 2024, Gopal et al.</rights><rights>Copyright © 2024, Gopal et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Gopal et al. 2024 Gopal et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-df939576e4ec04c9ac131a43f08e0d3ca1d58dbf1fb07fffb854991ec75c07563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166250/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166250/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38864033$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gopal, Kalashree</creatorcontrib><creatorcontrib>Howard, Jeremiah</creatorcontrib><creatorcontrib>Ramaraj, Shyamalee</creatorcontrib><creatorcontrib>Shroff, Ahaj H</creatorcontrib><creatorcontrib>Gamard, Christopher</creatorcontrib><title>An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course.</description><subject>Abdomen</subject><subject>Antigens</subject><subject>Bronchoscopy</subject><subject>Case reports</subject><subject>Cognitive ability</subject><subject>Diplopia</subject><subject>Dysphagia</subject><subject>Dyspnea</subject><subject>Esophagus</subject><subject>Eye examinations</subject><subject>Gastroenterology</subject><subject>Granulomas</subject><subject>Hospitalization</subject><subject>Hyponatremia</subject><subject>Insomnia</subject><subject>Leukocytes</subject><subject>Lymphatic system</subject><subject>Lymphoma</subject><subject>Magnetic resonance imaging</subject><subject>Neurology</subject><subject>Patients</subject><subject>Peripheral neuropathy</subject><subject>Primary care</subject><subject>Pulmonology</subject><subject>Sarcoidosis</subject><subject>Steroids</subject><subject>Tomography</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc1LXDEUxYNUVNSdawm46cKnN5O8fHRThkFtQTul1EVXIZN3U5-8ScbkpdD_vq8dK7are-H-OJxzDyEnDC6Uas2lrxlruZDAhNwhBzMmdaOZFm9e7fvkuJRHAGCgZqBgj-xzraUAzg_Ich7pfayluoF-zlgwjm7sU6Qp0E9Ycyou-9R3qfSF9pE6KkXzDV1ulkNH71x8R-d04QrSL7hJeTwiu8ENBY-f5yG5v776uvjQ3C5vPi7mt43nAGPTBcNNqyQK9CC8cZ5x5gQPoBE67h3rWt2tAgsrUCGElW6FMQy9aj2oVvJD8n6ru6mrNXZ-8p3dYDe5X7v80ybX238vsX-w39MPyxiTctbCpPD2WSGnp4pltOu-eBwGFzHVYjlIZZgwQk3o2X_oY6o5TvkmSnHNW6P4RJ1vKT99rWQML24Y2N9t2W1b9k9bE376OsEL_Lcb_gugIpBt</recordid><startdate>20240512</startdate><enddate>20240512</enddate><creator>Gopal, Kalashree</creator><creator>Howard, Jeremiah</creator><creator>Ramaraj, Shyamalee</creator><creator>Shroff, Ahaj H</creator><creator>Gamard, Christopher</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240512</creationdate><title>An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report</title><author>Gopal, Kalashree ; Howard, Jeremiah ; Ramaraj, Shyamalee ; Shroff, Ahaj H ; Gamard, Christopher</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c300t-df939576e4ec04c9ac131a43f08e0d3ca1d58dbf1fb07fffb854991ec75c07563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Antigens</topic><topic>Bronchoscopy</topic><topic>Case reports</topic><topic>Cognitive ability</topic><topic>Diplopia</topic><topic>Dysphagia</topic><topic>Dyspnea</topic><topic>Esophagus</topic><topic>Eye examinations</topic><topic>Gastroenterology</topic><topic>Granulomas</topic><topic>Hospitalization</topic><topic>Hyponatremia</topic><topic>Insomnia</topic><topic>Leukocytes</topic><topic>Lymphatic system</topic><topic>Lymphoma</topic><topic>Magnetic resonance imaging</topic><topic>Neurology</topic><topic>Patients</topic><topic>Peripheral neuropathy</topic><topic>Primary care</topic><topic>Pulmonology</topic><topic>Sarcoidosis</topic><topic>Steroids</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gopal, Kalashree</creatorcontrib><creatorcontrib>Howard, Jeremiah</creatorcontrib><creatorcontrib>Ramaraj, Shyamalee</creatorcontrib><creatorcontrib>Shroff, Ahaj H</creatorcontrib><creatorcontrib>Gamard, Christopher</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gopal, Kalashree</au><au>Howard, Jeremiah</au><au>Ramaraj, Shyamalee</au><au>Shroff, Ahaj H</au><au>Gamard, Christopher</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2024-05-12</date><risdate>2024</risdate><volume>16</volume><issue>5</issue><spage>e60146</spage><pages>e60146-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>38864033</pmid><doi>10.7759/cureus.60146</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2168-8184 |
ispartof | Curēus (Palo Alto, CA), 2024-05, Vol.16 (5), p.e60146 |
issn | 2168-8184 2168-8184 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11166250 |
source | PubMed Central Open Access; PubMed Central |
subjects | Abdomen Antigens Bronchoscopy Case reports Cognitive ability Diplopia Dysphagia Dyspnea Esophagus Eye examinations Gastroenterology Granulomas Hospitalization Hyponatremia Insomnia Leukocytes Lymphatic system Lymphoma Magnetic resonance imaging Neurology Patients Peripheral neuropathy Primary care Pulmonology Sarcoidosis Steroids Tomography |
title | An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T21%3A18%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20Unusual%20Presentation%20of%20Neurosarcoidosis%20in%20a%2064-Year-Old%20Man:%20A%20Case%20Report&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Gopal,%20Kalashree&rft.date=2024-05-12&rft.volume=16&rft.issue=5&rft.spage=e60146&rft.pages=e60146-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.60146&rft_dat=%3Cproquest_pubme%3E3067914947%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3073835973&rft_id=info:pmid/38864033&rfr_iscdi=true |