Evolving or immutable - phase I solid tumor trials in the era of precision oncology

In the era of precision oncology (PO), systemic therapies for patients (pts) with solid tumors have shifted from chemotherapy (CT) to targeted therapy (TT) and immunotherapy (IO). This systematic survey describes features of trials enrolling between 2010 and 2020, focusing on inclusion criteria, typ...

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Veröffentlicht in:	Investigational new drugs 2024-06, Vol.42 (3), p.326-334
Hauptverfasser:	Stockton, Shannon S., Ayers, G. Dan, Lee, Cody, Laferriere, Heather, Das, Satya, Berlin, Jordan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemotherapy Clinical trials Criteria Drug development Heterogeneity Immunotherapy Medicine Medicine & Public Health Oncology Pharmacology/Toxicology Precision medicine Solid tumors Tumors
Online-Zugang:	Volltext
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