Intervention design in cognitively impaired populations—Lessons learned from the OPTIMIZE deprescribing pragmatic trial

Background Polypharmacy is common in older adults with cognitive impairment and multiple chronic conditions, increasing risks of adverse drug events, hospitalization, and death. Deprescribing, the process of reducing or stopping potentially inappropriate medications, may improve outcomes. The OPTIMI...

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Veröffentlicht in:	Journal of the American Geriatrics Society (JAGS) 2023-03, Vol.71 (3), p.774-784
Hauptverfasser:	Sheehan, Orla C., Gleason, Kathy S., Bayliss, Elizabeth A., Green, Ariel R., Drace, Melanie L., Norton, Jonathan, Reeve, Emily, Shetterly, Susan M., Weffald, Linda A., Sawyer, Jennifer K., Maciejewski, Matthew L., Kraus, Courtney, Maiyani, Mahesh, Wolff, Jennifer, Boyd, Cynthia M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Caregivers Chronic illnesses Cognitive ability cognitive impairment deprescribing Deprescriptions Drug-Related Side Effects and Adverse Reactions Elder care Hospitalization Humans Intervention intervention delivery Older people Polypharmacy Potentially Inappropriate Medication List Pragmatic Clinical Trials as Topic
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