African swine fever virus infection regulates pyroptosis by cleaving gasdermin A via active caspase-3 and caspase-4

African swine fever, caused by the African swine fever virus (ASFV), is a viral hemorrhagic disease that affects domestic pigs and wild boars. ASFV infection causes extensive tissue damage, and the associated mechanism is poorly understood. Pyroptosis is characterized by the activation of inflammato...

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Veröffentlicht in:The Journal of biological chemistry 2024-06, Vol.300 (6), p.107307, Article 107307
Hauptverfasser: Li, Shuai, Song, Jie, Liu, Jia, Zhou, Shijun, Zhao, Gaihong, Li, Tingting, Huang, Li, Li, Jiangnan, Weng, Changjiang
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Sprache:eng
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