Bile acids repress E‐cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma

Although some kinds of bile acids have been implicated in colorectal cancer development, the mechanism of cancer progression remains unexplored in hepatobiliary cancer. From our personal results using complementary DNA microarray, we found that chenodeoxycholic acid (CDCA) induced Snail expression i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer science 2008-09, Vol.99 (9), p.1785-1792
Hauptverfasser:	Fukase, Koji, Ohtsuka, Hideo, Onogawa, Tohru, Oshio, Hiroshi, Ii, Takayuki, Mutoh, Mitsuhisa, Katayose, Yu, Rikiyama, Toshiki, Oikawa, Masaya, Motoi, Fuyuhiko, Egawa, Shinichi, Abe, Takaaki, Unno, Michiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile Duct Neoplasms - metabolism Bile Ducts, Intrahepatic - metabolism Biological and medical sciences Cadherins - metabolism Carcinoma, Hepatocellular - metabolism Cell Line, Tumor Chenodeoxycholic Acid - pharmacology Cholangiocarcinoma - metabolism Down-Regulation Female Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Agents - pharmacology Humans Lithocholic Acid - pharmacology Liver Neoplasms - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Neoplasm Invasiveness Original Snail Family Transcription Factors Transcription Factors - metabolism Tumors
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!