Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor‐infiltrating lymphocytes, tumor‐draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer

Although Th17 cells reportedly play critical roles in the development of autoimmunity and allergic reactions, information on Th17 cells in cancer‐bearing hosts is still limited. In the present study, we investigated the distribution of Th17 cells in relation to regulatory T cells (Treg) in the tumor...

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Veröffentlicht in:	Cancer science 2010-09, Vol.101 (9), p.1947-1954
Hauptverfasser:	Maruyama, Takanori, Kono, Koji, Mizukami, Yoshiki, Kawaguchi, Yoshihiko, Mimura, Kousaku, Watanabe, Mitsuaki, Izawa, Shinichirou, Fujii, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Female Flow Cytometry Forkhead Transcription Factors - metabolism Gastric cancer Gastric mucosa Gastroenterology. Liver. Pancreas. Abdomen Helper cells Humans Immunohistochemistry Immunoregulation Interleukin-17 - metabolism Interleukin-23 - metabolism Interleukins - metabolism Lymph nodes Lymph Nodes - immunology Lymph Nodes - metabolism Lymphocytes - immunology Lymphocytes - metabolism Lymphocytes T Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - metabolism Male Medical sciences Middle Aged Original Peripheral blood Stomach Neoplasms - blood Stomach Neoplasms - immunology Stomach Neoplasms - metabolism Stomach. Duodenum. Small intestine. Colon. Rectum. Anus T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Th1-Th2 Balance Th17 Cells - immunology Th17 Cells - metabolism Tumor-infiltrating lymphocytes Tumors
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