High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer

(Cancer Sci 2010; 101: 639–645) Gastric cancers show high frequency of DNA aneuploidy, a phenotype of chromosomal instability. It is suggested that the abnormal spindle assembly checkpoint is involved in DNA aneuploidy, but the underlying mechanism is still unclear. We studied the mechanism by asses...

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Veröffentlicht in:	Cancer science 2010-03, Vol.101 (3), p.639-645
Hauptverfasser:	Ando, Koji, Kakeji, Yosihiro, Kitao, Hiroyuki, Iimori, Makoto, Zhao, Yan, Yoshida, Rintaro, Oki, Eiji, Yoshinaga, Keiji, Matumoto, Takuya, Morita, Masaru, Sakaguchi, Yoshihisa, Maehara, Yoshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aneuploidy Biological and medical sciences Cell Line, Tumor Chromosome aberrations Disease Progression Female Humans Male Medical genetics Medical sciences Middle Aged Original Protein Serine-Threonine Kinases - analysis Protein Serine-Threonine Kinases - physiology Stomach Neoplasms - etiology Stomach Neoplasms - genetics Stomach Neoplasms - mortality Tumors
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