Up‐regulation of a BCL9‐related β‐catenin‐binding protein, B9L, in different stages of sporadic colorectal adenoma

Aberrant activation of Wnt signaling is a critical event in the development of human colorectal tumors. The aim of this study was to elucidate the role of B9L and its association with β‐catenin in each stage of the adenoma‐carcinoma sequence of human colorectal tumorigenesis. We investigated the exp...

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Veröffentlicht in:	Cancer science 2007-01, Vol.98 (1), p.83-87
Hauptverfasser:	Sakamoto, Ichiro, Ohwada, Susumu, Toya, Hiroyuki, Togo, Nozomi, Kashiwabara, Kenji, Oyama, Tetsunari, Nakajima, Takashi, Ito, Hideaki, Adachi, Shungo, Jigami, Takafumi, Akiyama, Tetsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenoma - metabolism Adenoma - pathology beta Catenin - metabolism Biological and medical sciences Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology DNA-Binding Proteins - biosynthesis Humans Immunohistochemistry Medical sciences Neoplasm Staging Original Reverse Transcriptase Polymerase Chain Reaction Transcription Factors - biosynthesis Tumors Up-Regulation
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