Expression of the c‐myc gene as a predictor of chemotherapy response and a prognostic factor in patients with ovarian cancer

The present study was conducted to determine whether and how expression of the c‐myc gene is related to the response to chemotherapy in patients with epithelial ovarian cancer. This study includes 101 consecutive patients with stage Ic to IV epithelial ovarian cancer who underwent primary surgery fo...

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Veröffentlicht in:	Cancer science 2004-05, Vol.95 (5), p.418-423
Hauptverfasser:	Iba, Takahiro, Kigawa, Junzo, Kanamori, Yasunobu, Itamochi, Hiroaki, Oishi, Tetsuro, Simada, Muneaki, Uegaki, Kazunori, Naniwa, Jun, Terakawa, Naoki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Apoptosis Biological and medical sciences Biotin Carboplatin - administration & dosage Chemotherapy Chemotherapy, Adjuvant Conformation DNA nucleotidylexotransferase Female Female genital diseases Gene expression Gene Expression Profiling Gene polymorphism Genes, myc Gynecology. Andrology. Obstetrics Humans Medical sciences Middle Aged Multivariate analysis Mutation Myc protein Ovarian cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - surgery p53 Protein Paclitaxel - administration & dosage Platinum Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational Predictive Value of Tests Prognosis Proto-Oncogene Proteins c-myc - biosynthesis Reverse transcription Surgery Survival Analysis Treatment Outcome Tumors
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