Reliability of the peptide nucleic acid‐locked nucleic acid polymerase chain reaction clamp‐based test for epidermal growth factor receptor mutations integrated into the clinical practice for non‐small cell lung cancers

Gefitinib is an inhibitor of the tyrosine kinase activity of epidermal growth factor receptor (EGFR). Accumulating evidence suggests that gefitinib may provide a survival benefit to EGFR mutation‐positive non‐small lung cancer patients. We have established a clinical test that can detect EGFR mutati...

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Veröffentlicht in:Cancer science 2007-02, Vol.98 (2), p.246-252
Hauptverfasser: Tanaka, Tomoaki, Nagai, Yoshiaki, Miyazawa, Hitoshi, Koyama, Nobuyuki, Matsuoka, Suguru, Sutani, Akihisa, Udagawa, Kiyoshi, Murayama, Yoshitake, Nagata, Makoto, Shimizu, Yoshihiko, Ikebuchi, Kenji, Kanazawa, Minoru, Kobayashi, Kunihiko, Hagiwara, Koichi
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Sprache:eng
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