Multiple tumor suppressor genes are increasingly methylated with age in non‐neoplastic gastric epithelia

A number of tumor suppressor and tumor‐related genes are silenced by promoter hypermethylation in gastric cancer. Hypermethylation is not restricted to cancer cells, but is also present in non‐neoplastic cells during aging. Such age‐related methylation in non‐neoplastic gastric epithelia is postulat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer science 2006-11, Vol.97 (11), p.1155-1158
Hauptverfasser:	So, Kanji, Tamura, Gen, Honda, Teiichiro, Homma, Naoyuki, Waki, Takayoshi, Togawa, Naoyuki, Nishizuka, Satoshi, Motoyama, Teiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Aging Biological and medical sciences Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Child Child, Preschool CpG Islands DNA Methylation Female Fundamental and applied biological sciences. Psychology Gastric Mucosa - metabolism Gene Silencing Genes, Tumor Suppressor Humans Infant Infant, Newborn Male Medical sciences Middle Aged Molecular and cellular biology Oligonucleotide Array Sequence Analysis Original Polymerase Chain Reaction Stomach Neoplasms - genetics Tumors
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!