Age and sex influence antibody profiles associated with tuberculosis progression

Antibody features vary with tuberculosis (TB) disease state. Whether clinical variables, such as age or sex, influence associations between Mycobacterium tuberculosis -specific antibody responses and disease state is not well explored. Here we profiled Mycobacterium tuberculosis -specific antibody r...

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Veröffentlicht in:	Nature microbiology 2024-06, Vol.9 (6), p.1513-1525
Hauptverfasser:	Davies, Leela R. L., Wang, Chuangqi, Steigler, Pia, Bowman, Kathryn A., Fischinger, Stephanie, Hatherill, Mark, Fisher, Michelle, Mbandi, Stanley Kimbung, Rodo, Miguel, Ottenhoff, Tom H. M., Dockrell, Hazel M., Sutherland, Jayne S., Mayanja-Kizza, Harriet, Boom, W. Henry, Walzl, Gerhard, Kaufmann, Stefan H. E., Nemes, Elisa, Scriba, Thomas J., Lauffenburger, Douglas, Alter, Galit, Fortune, Sarah M.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/1 631/250/2152/2153/1291 692/699/255/1856 Adolescent Adult Age Age Factors Antibodies Antibodies, Bacterial - blood Antibodies, Bacterial - immunology Antibody Formation - immunology Antibody response Biomedical and Life Sciences Cohort Studies Disease Progression Female Humans Infectious Diseases Life Sciences Male Medical Microbiology Microbiology Mycobacterium tuberculosis Mycobacterium tuberculosis - immunology Parasitology Sex Sex Factors South Africa - epidemiology Tuberculosis Tuberculosis - immunology Tuberculosis - microbiology Virology Young Adult
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