Global gene expression of fission yeast in response to cisplatin

The cellular response to the antitumor drug cisplatin is complex, and resistance is widespread. To gain insights into the global transcriptional response and mechanisms of resistance, we used microarrays to examine the fission yeast cell response to cisplatin. In two isogenic strains with differing...

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Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2004-09, Vol.61 (17), p.2253-2263
Hauptverfasser:	Gatti, L, Chen, D, Beretta, G L, Rustici, G, Carenini, N, Corna, E, Colangelo, D, Zunino, F, Bähler, J, Perego, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Bacteria Biodegradation Cadmium Cell cycle Cisplatin - pharmacology Deoxyribonucleic acid DNA DNA Damage Drug Resistance, Fungal Gene expression Gene Expression - drug effects Hydrogen-Ion Concentration Proteins Schizosaccharomyces - drug effects Schizosaccharomyces - genetics Schizosaccharomyces pombe Transcription, Genetic - drug effects Yeasts
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