Treatment of Inflammatory Bowel Disease using phosphorylcholine-presenting nanofibers engaging natural antibody responses

Inflammatory bowel disease (IBD) is a chronic disease that lacks a long-lasting and broadly effective therapy. Preexisting natural antibodies targeting the small molecule epitope phosphorylcholine (PC) have shown inherent benefits against infections and inflammation. Here, we present a PC-presenting...

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Veröffentlicht in:Nature biomedical engineering 2023-11, Vol.8 (5), p.628-649
Hauptverfasser: Curvino, Elizabeth J., Roe, Emily F., Freire Haddad, Helena, Anderson, Alexa R., Woodruff, Mia E., Votaw, Nicole L., Segura, Tatiana, Hale, Laura P., Collier, Joel H.
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Sprache:eng
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