Effect of sacubitril/valsartan on cardiac remodeling compared with other renin–angiotensin system inhibitors: a difference-in-difference analysis of propensity-score matched samples

Background In patients with heart failure with reduced ejection fraction (HFrEF), treatment with sacubitril–valsartan (S/V) may reverse left ventricular remodeling (rLVR). Whether this effect is superior to that induced by other renin–angiotensin system (RAS) inhibitors is not well known. Methods HF...

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Veröffentlicht in:	Clinical research in cardiology 2024-06, Vol.113 (6), p.856-865
Hauptverfasser:	Carluccio, Erberto, Dini, Frank L., Correale, Michele, Dattilo, Giuseppe, Ciccarelli, Michele, Vannuccini, Francesca, Sforna, Stefano, Pacileo, Giuseppe, Masarone, Daniele, Scelsi, Laura, Ghio, Stefano, Tocchetti, Carlo Gabriele, Mercurio, Valentina, Brunetti, Natale Daniele, Nodari, Savina, Ambrosio, Giuseppe, Palazzuoli, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aminobutyrates - therapeutic use Angiotensin Angiotensin Receptor Antagonists - therapeutic use Angiotensin-converting enzyme inhibitors Angiotensin-Converting Enzyme Inhibitors - therapeutic use Beta blockers Biphenyl Compounds Cardiology Congestive heart failure Drug Combinations Echocardiography Ejection fraction Enzyme inhibitors Female Heart Failure - drug therapy Heart Failure - physiopathology Humans Male Matching Medicine Medicine & Public Health Middle Aged Original Paper Peptidyl-dipeptidase A Propensity Score Renin Renin-Angiotensin System - drug effects Retrospective Studies Stroke Volume - drug effects Stroke Volume - physiology Tetrazoles - therapeutic use Treatment Outcome Valsartan - therapeutic use Ventricular Function, Left - drug effects Ventricular Function, Left - physiology Ventricular Remodeling - drug effects
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