The multifaceted role of periostin in priming the tumor microenvironments for tumor progression
Tumor microenvironment consists of tumor cells, stromal cells, extracellular matrix and a plethora of soluble components. The complex array of interactions between tumor cells and their surrounding tumor microenvironments contribute to the determination of the fate of tumor cells during tumorigenesi...
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| Veröffentlicht in: | Cellular and molecular life sciences : CMLS 2017-12, Vol.74 (23), p.4287-4291 |
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| creator | Cui, Dan Huang, Zhengjie Liu, Yingfu Ouyang, Gaoliang |
| description | Tumor microenvironment consists of tumor cells, stromal cells, extracellular matrix and a plethora of soluble components. The complex array of interactions between tumor cells and their surrounding tumor microenvironments contribute to the determination of the fate of tumor cells during tumorigenesis and metastasis. Matricellular protein periostin is generally absent in most adult tissues but is highly expressed in tumor microenvironments. Current evidence reveals that periostin plays a critical role in establishing and remodeling tumor microenvironments such as the metastatic niche, cancer stem cell niche, perivascular niche, pre-metastatic niche, fibrotic microenvironment and bone marrow microenvironment. Here, we summarize the current knowledge of the multifaceted role of periostin in the tumor microenvironments. |
| doi_str_mv | 10.1007/s00018-017-2646-2 |
| format | Article |
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The complex array of interactions between tumor cells and their surrounding tumor microenvironments contribute to the determination of the fate of tumor cells during tumorigenesis and metastasis. Matricellular protein periostin is generally absent in most adult tissues but is highly expressed in tumor microenvironments. Current evidence reveals that periostin plays a critical role in establishing and remodeling tumor microenvironments such as the metastatic niche, cancer stem cell niche, perivascular niche, pre-metastatic niche, fibrotic microenvironment and bone marrow microenvironment. Here, we summarize the current knowledge of the multifaceted role of periostin in the tumor microenvironments.</description><identifier>ISSN: 1420-682X</identifier><identifier>EISSN: 1420-9071</identifier><identifier>DOI: 10.1007/s00018-017-2646-2</identifier><identifier>PMID: 28884337</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Biochemistry ; Biomedical and Life Sciences ; Biomedicine ; Bone cancer ; Bone marrow ; Bone Marrow - metabolism ; Bone Marrow - pathology ; Cancer ; Cell adhesion & migration ; Cell Adhesion Molecules - genetics ; Cell Adhesion Molecules - metabolism ; Cell Biology ; Cell Communication ; Cells ; Disease Progression ; Extracellular matrix ; Extracellular Matrix - metabolism ; Extracellular Matrix - pathology ; Fibroblasts - metabolism ; Fibroblasts - pathology ; Fibrosis ; Gene Expression Regulation, Neoplastic ; Humans ; Life Sciences ; Metastases ; Metastasis ; Microenvironments ; Multi-Author Review ; Neoplasm Metastasis ; Neoplasm Proteins - genetics ; Neoplasm Proteins - metabolism ; Neoplasms - genetics ; Neoplasms - metabolism ; Neoplasms - pathology ; Neoplastic Stem Cells - metabolism ; Neoplastic Stem Cells - pathology ; Priming ; Stem Cell Niche - genetics ; Stem cells ; Stromal cells ; Stromal Cells - metabolism ; Stromal Cells - pathology ; Tumor cells ; Tumor Microenvironment - genetics ; Tumorigenesis ; Tumors</subject><ispartof>Cellular and molecular life sciences : CMLS, 2017-12, Vol.74 (23), p.4287-4291</ispartof><rights>Springer International Publishing AG 2017</rights><rights>Cellular and Molecular Life Sciences is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-b1d9efa9aed6cea97e8638ebf5726f5185b385681f5846f83792b1794293c7683</citedby><cites>FETCH-LOGICAL-c494t-b1d9efa9aed6cea97e8638ebf5726f5185b385681f5846f83792b1794293c7683</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107730/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107730/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28884337$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cui, Dan</creatorcontrib><creatorcontrib>Huang, Zhengjie</creatorcontrib><creatorcontrib>Liu, Yingfu</creatorcontrib><creatorcontrib>Ouyang, Gaoliang</creatorcontrib><title>The multifaceted role of periostin in priming the tumor microenvironments for tumor progression</title><title>Cellular and molecular life sciences : CMLS</title><addtitle>Cell. Mol. Life Sci</addtitle><addtitle>Cell Mol Life Sci</addtitle><description>Tumor microenvironment consists of tumor cells, stromal cells, extracellular matrix and a plethora of soluble components. The complex array of interactions between tumor cells and their surrounding tumor microenvironments contribute to the determination of the fate of tumor cells during tumorigenesis and metastasis. Matricellular protein periostin is generally absent in most adult tissues but is highly expressed in tumor microenvironments. Current evidence reveals that periostin plays a critical role in establishing and remodeling tumor microenvironments such as the metastatic niche, cancer stem cell niche, perivascular niche, pre-metastatic niche, fibrotic microenvironment and bone marrow microenvironment. Here, we summarize the current knowledge of the multifaceted role of periostin in the tumor microenvironments.</description><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bone cancer</subject><subject>Bone marrow</subject><subject>Bone Marrow - metabolism</subject><subject>Bone Marrow - pathology</subject><subject>Cancer</subject><subject>Cell adhesion & migration</subject><subject>Cell Adhesion Molecules - genetics</subject><subject>Cell Adhesion Molecules - metabolism</subject><subject>Cell Biology</subject><subject>Cell Communication</subject><subject>Cells</subject><subject>Disease Progression</subject><subject>Extracellular matrix</subject><subject>Extracellular Matrix - metabolism</subject><subject>Extracellular Matrix - pathology</subject><subject>Fibroblasts - metabolism</subject><subject>Fibroblasts - pathology</subject><subject>Fibrosis</subject><subject>Gene Expression Regulation, Neoplastic</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Metastases</subject><subject>Metastasis</subject><subject>Microenvironments</subject><subject>Multi-Author Review</subject><subject>Neoplasm Metastasis</subject><subject>Neoplasm Proteins - genetics</subject><subject>Neoplasm Proteins - metabolism</subject><subject>Neoplasms - genetics</subject><subject>Neoplasms - metabolism</subject><subject>Neoplasms - pathology</subject><subject>Neoplastic Stem Cells - metabolism</subject><subject>Neoplastic Stem Cells - pathology</subject><subject>Priming</subject><subject>Stem Cell Niche - genetics</subject><subject>Stem cells</subject><subject>Stromal cells</subject><subject>Stromal Cells - metabolism</subject><subject>Stromal Cells - pathology</subject><subject>Tumor cells</subject><subject>Tumor Microenvironment - genetics</subject><subject>Tumorigenesis</subject><subject>Tumors</subject><issn>1420-682X</issn><issn>1420-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kUtr3DAUhUVJ6STT_oBugiGbbtzqYb1WIQxpUgh0k0J3QvZcTRRsaSLZA_n31eBJmAQKAgmdT-feq4PQV4K_E4zlj4wxJqrGRNZUNKKmH9ApaSiuNZbk5HAWiv5doLOcHwvMFRWf0IIqpRrG5Cky9w9QDVM_emc7GGFdpdhDFV21heRjHn2oytomP_iwqcZCj9MQUzX4LkUIO59iGCCMuXLldta2KW4S5Oxj-Iw-Ottn-HLYl-jPz-v71W199_vm1-rqru4a3Yx1S9YanNUW1qIDqyUowRS0jksqHCeKt0xxoYjjqhFOMalpS6RuqGadFIot0eXsu53aAdZd6SjZ3uz7tunZROvNWyX4B7OJO0MIwVIyXBy-HRxSfJogj2bwuYO-twHilA3RTHLKNacFvXiHPsYphTJfobiUmGreFIrMVPmonBO4124INvv8zJyfKfmZfX5m73x-PMbri5fACkBnIBcpbCAdlf6v6z9nKKez</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Cui, Dan</creator><creator>Huang, Zhengjie</creator><creator>Liu, Yingfu</creator><creator>Ouyang, Gaoliang</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SS</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20171201</creationdate><title>The multifaceted role of periostin in priming the tumor microenvironments for tumor progression</title><author>Cui, Dan ; Huang, Zhengjie ; Liu, Yingfu ; Ouyang, Gaoliang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-b1d9efa9aed6cea97e8638ebf5726f5185b385681f5846f83792b1794293c7683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bone cancer</topic><topic>Bone marrow</topic><topic>Bone Marrow - metabolism</topic><topic>Bone Marrow - pathology</topic><topic>Cancer</topic><topic>Cell adhesion & migration</topic><topic>Cell Adhesion Molecules - genetics</topic><topic>Cell Adhesion Molecules - metabolism</topic><topic>Cell Biology</topic><topic>Cell Communication</topic><topic>Cells</topic><topic>Disease Progression</topic><topic>Extracellular matrix</topic><topic>Extracellular Matrix - metabolism</topic><topic>Extracellular Matrix - pathology</topic><topic>Fibroblasts - metabolism</topic><topic>Fibroblasts - pathology</topic><topic>Fibrosis</topic><topic>Gene Expression Regulation, Neoplastic</topic><topic>Humans</topic><topic>Life Sciences</topic><topic>Metastases</topic><topic>Metastasis</topic><topic>Microenvironments</topic><topic>Multi-Author Review</topic><topic>Neoplasm Metastasis</topic><topic>Neoplasm Proteins - genetics</topic><topic>Neoplasm Proteins - metabolism</topic><topic>Neoplasms - genetics</topic><topic>Neoplasms - metabolism</topic><topic>Neoplasms - pathology</topic><topic>Neoplastic Stem Cells - metabolism</topic><topic>Neoplastic Stem Cells - pathology</topic><topic>Priming</topic><topic>Stem Cell Niche - genetics</topic><topic>Stem cells</topic><topic>Stromal cells</topic><topic>Stromal Cells - metabolism</topic><topic>Stromal Cells - pathology</topic><topic>Tumor cells</topic><topic>Tumor Microenvironment - genetics</topic><topic>Tumorigenesis</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cui, Dan</creatorcontrib><creatorcontrib>Huang, Zhengjie</creatorcontrib><creatorcontrib>Liu, Yingfu</creatorcontrib><creatorcontrib>Ouyang, Gaoliang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cellular and molecular life sciences : CMLS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cui, Dan</au><au>Huang, Zhengjie</au><au>Liu, Yingfu</au><au>Ouyang, Gaoliang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The multifaceted role of periostin in priming the tumor microenvironments for tumor progression</atitle><jtitle>Cellular and molecular life sciences : CMLS</jtitle><stitle>Cell. Mol. Life Sci</stitle><addtitle>Cell Mol Life Sci</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>74</volume><issue>23</issue><spage>4287</spage><epage>4291</epage><pages>4287-4291</pages><issn>1420-682X</issn><eissn>1420-9071</eissn><abstract>Tumor microenvironment consists of tumor cells, stromal cells, extracellular matrix and a plethora of soluble components. The complex array of interactions between tumor cells and their surrounding tumor microenvironments contribute to the determination of the fate of tumor cells during tumorigenesis and metastasis. Matricellular protein periostin is generally absent in most adult tissues but is highly expressed in tumor microenvironments. Current evidence reveals that periostin plays a critical role in establishing and remodeling tumor microenvironments such as the metastatic niche, cancer stem cell niche, perivascular niche, pre-metastatic niche, fibrotic microenvironment and bone marrow microenvironment. Here, we summarize the current knowledge of the multifaceted role of periostin in the tumor microenvironments.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>28884337</pmid><doi>10.1007/s00018-017-2646-2</doi><tpages>5</tpages></addata></record> |
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| subjects | Biochemistry Biomedical and Life Sciences Biomedicine Bone cancer Bone marrow Bone Marrow - metabolism Bone Marrow - pathology Cancer Cell adhesion & migration Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Cell Biology Cell Communication Cells Disease Progression Extracellular matrix Extracellular Matrix - metabolism Extracellular Matrix - pathology Fibroblasts - metabolism Fibroblasts - pathology Fibrosis Gene Expression Regulation, Neoplastic Humans Life Sciences Metastases Metastasis Microenvironments Multi-Author Review Neoplasm Metastasis Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Priming Stem Cell Niche - genetics Stem cells Stromal cells Stromal Cells - metabolism Stromal Cells - pathology Tumor cells Tumor Microenvironment - genetics Tumorigenesis Tumors |
| title | The multifaceted role of periostin in priming the tumor microenvironments for tumor progression |
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