The multifaceted role of reactive oxygen species in tumorigenesis

Redox homeostasis is an essential requirement of the biological systems for performing various normal cellular functions including cellular growth, differentiation, senescence, survival and aging in humans. The changes in the basal levels of reactive oxygen species (ROS) are detrimental to cells and...

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Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2020-11, Vol.77 (22), p.4459-4483
Hauptverfasser:	Kirtonia, Anuradha, Sethi, Gautam, Garg, Manoj
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Angiogenesis Animals Antineoplastic drugs Antitumor activity Antitumor agents Biochemistry Biomedical and Life Sciences Biomedicine Cancer Carcinogenesis - metabolism Cell Biology Chemotherapy Diabetes mellitus Drug resistance Ferroptosis Homeostasis Humans Immunosuppressive agents Immunotherapy Life Sciences Metastases Metastasis Mutation Neoplasm Recurrence, Local - metabolism Neoplasms - metabolism Neoplasms - pathology Oxidation resistance Oxidation-Reduction Oxidative stress Oxidative Stress - physiology Patients Radiation therapy Reactive oxygen species Reactive Oxygen Species - metabolism Review Senescence Signal Transduction - physiology Stem cells Surgery Survival Telomeres Tumor cells Tumorigenesis
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